Global Patent Index - EP 0973737 A4

EP 0973737 A4 20000426 - EFFICIENT SYNTHESIS OF A CHIRAL MEDIATOR

Title (en)

EFFICIENT SYNTHESIS OF A CHIRAL MEDIATOR

Title (de)

EFFIZIENTE SYNTHESE EINES CHIRALEN MEDIATORS

Title (fr)

SYNTHESE EFFICACE D'UN MEDIATEUR CHIRAL

Publication

EP 0973737 A4 20000426 (EN)

Application

EP 98903459 A 19980106

Priority

  • GB 9704194 A 19970228
  • GB 9710393 A 19970520
  • US 9800578 W 19980106
  • US 3492697 P 19970110
  • US 4202197 P 19970417
  • US 4516797 P 19970430

Abstract (en)

[origin: WO9830540A1] An efficient method for the quantitative preparation and isolation of a compound of formula (I) or its enantiomer, a chiral mediator used in enantioselective synthesis.

IPC 1-7

C07D 205/04; C07D 209/44; C07D 211/14; C07D 221/04; C07D 221/14; C07D 295/08; C07D 295/088; C07D 295/092; C07D 295/096

IPC 8 full level

C07D 295/08 (2006.01); C07D 205/04 (2006.01); C07D 209/44 (2006.01); C07D 221/06 (2006.01); C07D 221/14 (2006.01); C07D 295/084 (2006.01); C07D 295/096 (2006.01)

CPC (source: EP)

C07D 205/04 (2013.01); C07D 209/44 (2013.01); C07D 221/14 (2013.01); C07D 295/092 (2013.01); C07D 295/096 (2013.01); C07B 2200/07 (2013.01); C07C 2602/08 (2017.05)

Citation (search report)

  • [Y] WO 9630339 A1 19961003 - PFIZER [US], et al
  • [DA] WO 9637457 A1 19961128 - MERCK & CO INC [US]
  • [A] AZIZOV A M ET AL: "Complete alkylation of 2-aminoethanol in the presence of sodium hydroxide", AZERB. KHIM. ZH. (AZKZAU,00052531);1985; (6); PP.61-5, Azerb. Inzh.-Stroit. Inst.;Baku; USSR (SU), XP002131296
  • [XY] BROWN E ET AL: "Asymmetric reductions of ketones using lithium aluminum hydride modified with N,N-dialkyl derivatives of (R)-(-)-2-aminobutan-1-ol", TETRAHEDRON: ASYMMETRY (TASYE3,09574166);1991; VOL.2 (5); PP.339-42, Fac. Sci.;Lab. Synth. Org.; Le Mans; 72017; Fr. (FR), XP000872930
  • [Y] PIERCE M E ET AL: "Practical Asymmetric Synthesis of Efavirenz (DMP 266), an HIV-1 Reverse Transcriptase Inhibitor", J. ORG. CHEM. (JOCEAH,00223263);1998; VOL.63 (23); PP.8536-8543, The DuPont Pharmaceuticals Company;Chemical Process R&D Department Process Research Facility; Deepwater; 08023-0999; NJ; USA (US), XP000881116
  • See also references of WO 9830540A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9830540 A1 19980716; AU 6022598 A 19980803; AU 732430 B2 20010426; CA 2276074 A1 19980716; EP 0973737 A1 20000126; EP 0973737 A4 20000426; JP 2000507970 A 20000627

DOCDB simple family (application)

US 9800578 W 19980106; AU 6022598 A 19980106; CA 2276074 A 19980106; EP 98903459 A 19980106; JP 53122298 A 19980106