Global Patent Index - EP 0973904 A1

EP 0973904 A1 2000-01-26 - COMPOSITIONS AND USE OF M-CSF-alpha

Title (en)

COMPOSITIONS AND USE OF M-CSF-alpha

Title (de)

Zusammensetzungen und Verwendungen von M-CSF-alpha

Title (fr)

COMPOSITIONS ET UTILISATIONS DE M-CSF-alpha

Publication

EP 0973904 A1 (EN)

Application

EP 98910322 A

Priority

  • US 9804802 W
  • US 3858397 P

Abstract (en)

[origin: WO9839449A1] The invention is a method and composition for reducing a population of diseased cells by administration of a gene delivery vehicle capable of expressing an M-CSF alpha mutant having a decreased capacity to be proteolytically processed and released from a cell membrane. The invention is also a combination of therapeutic agents including gene delivery vehicles expressing M-CSF alpha or an M-CSF alpha mutant in combination, for example, either with a soluble M-CSF, an M-CSF alpha convertase inhibitor, or a gene delivery vehicle expressing prodrug activator such as thymidine kinase followed by administration of the prodrug.

IPC 1-7 (main, further and additional classification)

C12N 15/27; C07K 14/53; A61K 48/00; A61K 38/19

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/53 (2006.01); C12N 5/10 (2006.01); C12N 15/27 (2006.01)

CPC (invention and additional information)

C07K 14/53 (2013.01); A61K 38/193 (2013.01); A61K 48/00 (2013.01); C12N 2799/022 (2013.01); Y02A 50/409 (2018.01)

Combination set (CPC)

A61K 38/193 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9839449 A1 19980911; AU 6458898 A 19980922; EP 0973904 A1 20000126; JP 2001517079 A 20011002

INPADOC legal status


2002-04-17 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20011002

2000-01-26 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990923

2000-01-26 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE