EP 0975330 A1 20000202 - PAIN REDUCING PARENTERAL LIPOSOME FORMULATION
Title (en)
PAIN REDUCING PARENTERAL LIPOSOME FORMULATION
Title (de)
PARENTERALE LIPOSOMENFORMULIERUNG ZUR SCHMERZEN LINDERUNG
Title (fr)
FORMULATION ANALGESIQUE A ADMINISTRATION PARENTERALE ENCAPSULEE DANS UN LIPOSOME
Publication
Application
Priority
- US 9801430 W 19980126
- US 79406497 A 19970204
- US 360698 A 19980107
Abstract (en)
[origin: WO9833482A1] Disclosed is an invention directed towards pain-reducing parenteral formulations comprising a macrolide drug entrapped in a liposome vesicle. The macrolide drug is selected from the group consisting of derivatives of erythromycins A, B, C and D; clarithromycin; azithromycin; dirithromycin; josamycin; midecamycin; kitasamycin; roxithromycin; rokitamycin; oleandomycin; miocamycin; flurithromycin; rosaramicin; 8,9-anhydro-4''-deoxy-3'-N-desmethyl-3'-N-ethylerythromycin B 6,9-hemiacetal; 8,9-anhydro-4''-deoxy-3'-N-desmethyl-3'-N-ethylerythromycin A 6,9-hemiacetal; and 11-amino-11-deoxy-3-oxo-5-O-desosaminyl-6-O-[1'-3'-quinolyl-2'-propenyl]-erythronolide A 11,12-cyclic carbamate. The formulations of the invention are effective in substantially reducing the pain at the injection site typically associated with the injection of macrolide antibiotics.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 31/7048 (2006.01); A61K 47/10 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2006.01); A61K 47/22 (2006.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/36 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP)
A61K 9/127 (2013.01); A61K 31/7048 (2013.01); A61P 31/04 (2017.12)
Citation (search report)
See references of WO 9833482A1
Designated contracting state (EPC)
DE FR GB IT
DOCDB simple family (publication)
WO 9833482 A1 19980806; AU 6041498 A 19980825; CA 2279259 A1 19980806; EP 0975330 A1 20000202; JP 2001511780 A 20010814
DOCDB simple family (application)
US 9801430 W 19980126; AU 6041498 A 19980126; CA 2279259 A 19980126; EP 98903718 A 19980126; JP 53298498 A 19980126