Global Patent Index - EP 0975330 A1

EP 0975330 A1 2000-02-02 - PAIN REDUCING PARENTERAL LIPOSOME FORMULATION

Title (en)

PAIN REDUCING PARENTERAL LIPOSOME FORMULATION

Title (de)

PARENTERALE LIPOSOMENFORMULIERUNG ZUR SCHMERZEN LINDERUNG

Title (fr)

FORMULATION ANALGESIQUE A ADMINISTRATION PARENTERALE ENCAPSULEE DANS UN LIPOSOME

Publication

EP 0975330 A1 (EN)

Application

EP 98903718 A

Priority

  • US 9801430 W
  • US 79406497 A
  • US 360698 A

Abstract (en)

[origin: WO9833482A1] Disclosed is an invention directed towards pain-reducing parenteral formulations comprising a macrolide drug entrapped in a liposome vesicle. The macrolide drug is selected from the group consisting of derivatives of erythromycins A, B, C and D; clarithromycin; azithromycin; dirithromycin; josamycin; midecamycin; kitasamycin; roxithromycin; rokitamycin; oleandomycin; miocamycin; flurithromycin; rosaramicin; 8,9-anhydro-4''-deoxy-3'-N-desmethyl-3'-N-ethylerythromycin B 6,9-hemiacetal; 8,9-anhydro-4''-deoxy-3'-N-desmethyl-3'-N-ethylerythromycin A 6,9-hemiacetal; and 11-amino-11-deoxy-3-oxo-5-O-desosaminyl-6-O-[1'-3'-quinolyl-2'-propenyl]-erythronolide A 11,12-cyclic carbamate. The formulations of the invention are effective in substantially reducing the pain at the injection site typically associated with the injection of macrolide antibiotics.

IPC 1-7 (main, further and additional classification)

A61K 9/127; A61K 31/70

IPC 8 full level (invention and additional information)

A61K 9/127 (2006.01); A61K 31/7048 (2006.01); A61K 47/10 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2006.01); A61K 47/22 (2006.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/36 (2006.01); A61P 31/04 (2006.01)

CPC (invention and additional information)

A61K 31/7048 (2013.01); A61K 9/127 (2013.01)

Citation (search report)

See references of WO 9833482A1

Designated contracting state (EPC)

DE FR GB IT

EPO simple patent family

WO 9833482 A1 19980806; AU 6041498 A 19980825; CA 2279259 A1 19980806; EP 0975330 A1 20000202; JP 2001511780 A 20010814

INPADOC legal status


2003-02-12 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020801

2002-06-05 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020416

2000-02-02 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990824

2000-02-02 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): DE FR GB IT