Global Patent Index - EP 0975331 A1

EP 0975331 A1 2000-02-02 - A NOVEL BIOADHESIVE DRUG DELIVERY SYSTEM BASED ON LIQUID CRYSTALS

Title (en)

A NOVEL BIOADHESIVE DRUG DELIVERY SYSTEM BASED ON LIQUID CRYSTALS

Title (de)

NEUES BIOADHÄSIVES ARZNEISTOFFABGABESYSTEM AUF BASIS VON FLÜSSIGKRISTALLEN

Title (fr)

NOUVEAU SYSTEME BIOADHESIF D'ADMINISTRATION DE MEDICAMENTS BASE SUR DES CRISTAUX LIQUIDES

Publication

EP 0975331 A1 (EN)

Application

EP 98914850 A

Priority

  • DK 9800159 W
  • DK 43597 A

Abstract (en)

[origin: WO9847487A1] A drug delivery system containing a liquid crystalline phase such as a cubic, a hexagonal, a reverse hexagonal, a lamellar, a micellar and a reverse micellar liquid crystalline phase. The compositions are unique in that they, as delivery system, contain A) a substance which is capable of generating a liquid crystalline phase and providing suitable biopharmaceutical properties like e.g. suitable release of the active substance and bioadhesive properties, and B) at least another substance which without having any substantially negative effect on the biopharmaceutical properties provided by the substance mentioned above under A) either takes part in the formation of a liquid crystalline phase or dilutes the proportion of liquid crystalline phase in the composition while still maintaining suitable biopharmaceutical properties and a suitable storage stability. Examples of substances A) are fatty acid esters like e.g. glycerylmonooleate and glycerylmonolinoleate and examples of substances B) are e.g. structurants like phospholipids and tocopherols and/or pharmaceutically acceptable excipients.

IPC 1-7 (main, further and additional classification)

A61K 9/127

IPC 8 full level (invention and additional information)

A61K 9/127 (2006.01)

CPC (invention and additional information)

A61K 9/1274 (2013.01)

Citation (search report)

See references of WO 9847487A1

Designated contracting state (EPC)

CH DE DK ES FR GB IT LI NL

EPO simple patent family

WO 9847487 A1 19981029; AU 6919598 A 19981113; CA 2286052 A1 19981029; EP 0975331 A1 20000202; JP 2001524958 A 20011204

INPADOC legal status


2003-09-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030220

2002-09-25 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020809

2000-03-29 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: GS DEVELOPMENT AB

2000-02-02 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991117

2000-02-02 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): CH DE DK ES FR GB IT LI NL