EP 0975332 A1 20000202 - IMPROVED METHODS OF DELIVERY USING CATIONIC LIPIDS AND HELPER LIPIDS
Title (en)
IMPROVED METHODS OF DELIVERY USING CATIONIC LIPIDS AND HELPER LIPIDS
Title (de)
VERBESSERTE VERFAHREN ZUR VERABREICHUNG UNTER VERWENDUNG VON KATIONISCHEN LIPIDEN UND HELFER-LIPIDEN
Title (fr)
METHODES AMELIOREES DE TRANSPORT UTILISANT DES LIPIDES CATIONIQUES ET DES LIPIDES ASSISTANTS
Publication
Application
Priority
- US 9806606 W 19980403
- US 83274997 A 19970404
Abstract (en)
[origin: WO9844909A1] Methods and compositions are provided for the introduction of polyanionic molecules, in particular, nucleic acids, into mammalian cells using certain phosphatidyl ethanolamines as helper lipids in conjunction with various cationic lipids. In particular, cationic lipid-mediated transfection of mammalian cells is improved by the use of lipid carriers comprising DLPE or DiPPE and cationic lipids.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 48/00 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP)
A61K 9/1272 (2013.01); A61K 47/544 (2017.07); A61K 48/00 (2013.01); C12N 15/88 (2013.01)
Citation (search report)
See references of WO 9844909A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9844909 A1 19981015; AU 6949098 A 19981030; CA 2286739 A1 19981015; EP 0975332 A1 20000202
DOCDB simple family (application)
US 9806606 W 19980403; AU 6949098 A 19980403; CA 2286739 A 19980403; EP 98915263 A 19980403