Global patent index - EP 0975628 A1

EP 0975628 A1 2000-02-02 - PREVENTION OF BREAST CANCER WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS

Title (en)

PREVENTION OF BREAST CANCER WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS

Title (de)

VORBEUGUNG VON BRUSTKREBS MIT HILFE EINES SELEKTIVEN MODULATORS DES ÖSTROGEN-REZEPTORS

Title (fr)

PROPHYLAXIE DU CARCINOME MAMMAIRE AU MOYEN DE MODULATEURS SELECTIFS DU RECEPTEUR DES OESTROGENES

Publication

EP 0975628 A1 (EN)

Application

EP 98915368 A

Priority

  • US 9806989 W
  • US 4311897 P

Abstract (en)

[origin: WO9845286A1] The present invention provides a method of preventing breast carcinoma or cancer in a patient comprising administering a therapeutically effective amount of a compound having the structure (I) in which R<1> and R<2> are independently hydroxy or alkoxy of one to four carbon atoms; and R<3> and R<4> are independently methyl or ethyl, or R<3> and R<4>, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.

IPC 1-7 (main, further and additional classification)

C07D 409/12; A61K 31/38; A61K 31/535

IPC 8 full level (invention and additional information)

A61K 31/4025 (2006.01); A61K 31/4535 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); C07D 333/64 (2006.01)

CPC (invention and additional information)

C07D 333/64 (2013.01); A61K 31/4535 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9845286 A1 19981015; AU 6957398 A 19981030; CA 2286207 A1 19981015; CN 1259945 A 20000712; EP 0975628 A1 20000202; EP 0975628 A4 20010321; HU 0001845 A2 20010628; ID 23653 A 20000511; IL 132279 D0 20010319; JP 2001518897 A 20011016; KR 20010006215 A 20010126; NO 994902 A 19991207; NO 994902 D0 19991008; PL 336206 A1 20000605; TR 9903244 T2 20000522; ZA 9802818 B 19991004

INPADOC legal status

2003-05-07 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20021104

2001-03-21 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20010205

2001-03-21 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-03-21 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- Free Format Text: 7C 07D 409/12 A, 7A 61K 31/535 B, 7A 61K 31/38 B, 7A 61K 31/445 B

2000-02-02 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991015

2000-02-02 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-02-02 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 19991015;LT PAYMENT 19991015;LV PAYMENT 19991015;RO PAYMENT 19991015;SI PAYMENT 19991015