EP 0975628 A1 20000202 - PREVENTION OF BREAST CANCER WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS
Title (en)
PREVENTION OF BREAST CANCER WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS
Title (de)
VORBEUGUNG VON BRUSTKREBS MIT HILFE EINES SELEKTIVEN MODULATORS DES ÖSTROGEN-REZEPTORS
Title (fr)
PROPHYLAXIE DU CARCINOME MAMMAIRE AU MOYEN DE MODULATEURS SELECTIFS DU RECEPTEUR DES OESTROGENES
Publication
Application
Priority
- US 9806989 W 19980407
- US 4311897 P 19970409
Abstract (en)
[origin: WO9845286A1] The present invention provides a method of preventing breast carcinoma or cancer in a patient comprising administering a therapeutically effective amount of a compound having the structure (I) in which R<1> and R<2> are independently hydroxy or alkoxy of one to four carbon atoms; and R<3> and R<4> are independently methyl or ethyl, or R<3> and R<4>, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.
IPC 1-7
IPC 8 full level
A61K 31/4025 (2006.01); A61K 31/4535 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); C07D 333/64 (2006.01)
CPC (source: EP KR)
A61K 31/38 (2013.01 - KR); A61K 31/4535 (2013.01 - EP); A61P 35/00 (2018.01 - EP); C07D 333/64 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9845286 A1 19981015; AU 6957398 A 19981030; CA 2286207 A1 19981015; CN 1259945 A 20000712; EA 199900910 A1 20000424; EP 0975628 A1 20000202; EP 0975628 A4 20010321; HU P0001845 A2 20010628; ID 23653 A 20000511; IL 132279 A0 20010319; JP 2001518897 A 20011016; KR 20010006215 A 20010126; NO 994902 D0 19991008; NO 994902 L 19991207; PL 336206 A1 20000605; TR 199903244 T2 20000522; ZA 982818 B 19991004
DOCDB simple family (application)
US 9806989 W 19980407; AU 6957398 A 19980407; CA 2286207 A 19980407; CN 98805957 A 19980407; EA 199900910 A 19980407; EP 98915368 A 19980407; HU P0001845 A 19980407; ID 991189 A 19980407; IL 13227998 A 19980407; JP 54309098 A 19980407; KR 19997009295 A 19991009; NO 994902 A 19991008; PL 33620698 A 19980407; TR 9903244 T 19980407; ZA 982818 A 19980402