Global patent index - EP 0975629 A1

EP 0975629 A1 2000-02-02 - TREATMENT OR PROPHYLAXIS OF PROSTATIC CANCER AND BENIGN PROSTATIC HYPERPLASIA WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS

Title (en)

TREATMENT OR PROPHYLAXIS OF PROSTATIC CANCER AND BENIGN PROSTATIC HYPERPLASIA WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS

Title (de)

BEHANDLUNG ODER PROPHYLAXE VON PROSTATAKREBS UND DER GUTARTIGEN PROSTATEHYPERPLASIEMIT SELEKTIVEN ÖSTROGENREZEPTOR-MODULATOREN

Title (fr)

TRAITEMENT OU PROPHYLAXIE DU CANCER DE LA PROSTATE ET DE L'HYPERPLASIE PROSTATIQUE BENIGNE A L'AIDE DE MODULATEURS SELECTIFS DES RECEPTEURS D'OESTROGENES

Publication

EP 0975629 A1 (EN)

Application

EP 98915488 A

Priority

  • US 9807274 W
  • US 4322397 P

Abstract (en)

[origin: WO9845288A1] The present invention provides a method for the treatment or prophylaxis of benign prostatic hyperplasia or prostatic cancer in a patient in need of such treatment comprising administering a selective estrogen receptor modulating compound of formula (I), in which R<1> and R<2> are independently hydroxy and alkoxy of one to four carbon atoms; and R<3> and R<4> are independently methyl or ethyl, or R<3> and R<4>, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.

IPC 1-7 (main, further and additional classification)

C07D 409/12; A61K 31/38; A61K 31/535

IPC 8 full level (invention and additional information)

C07D 333/64 (2006.01); A61K 31/381 (2006.01); A61K 31/4025 (2006.01); A61K 31/4535 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 5/30 (2006.01); A61P 13/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)

CPC (invention and additional information)

A61K 31/5377 (2013.01); A61K 31/381 (2013.01); A61K 31/4025 (2013.01); A61K 31/4535 (2013.01); A61K 31/55 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9845288 A1 19981015; AU 6966198 A 19981030; BR 9808515 A 20010619; CA 2286204 A1 19981015; CN 1259944 A 20000712; EP 0975629 A1 20000202; EP 0975629 A4 20010321; HU 0003589 A2 20020128; HU 0003589 A3 20020228; ID 24358 A 20000713; IL 132277 D0 20010319; JP 2001518900 A 20011016; KR 20010006218 A 20010126; NO 994903 A 19991209; NO 994903 D0 19991008; PL 336205 A1 20000605; TR 9902701 T2 20000221; ZA 9802819 B 19991004

INPADOC legal status

2003-05-07 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20021104

2001-03-21 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20010205

2001-03-21 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-02-02 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991015

2000-02-02 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-02-02 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 19991015;LT PAYMENT 19991015;LV PAYMENT 19991015;RO PAYMENT 19991015;SI PAYMENT 19991015