EP 0975662 A1 20000202 - HEPATITIS C NS3 PROTEASE INHIBITORS
Title (en)
HEPATITIS C NS3 PROTEASE INHIBITORS
Title (de)
HEPATITIS C NS3 PROTEASE INHIBITORE
Title (fr)
INHIBITEURS DE PROTEASE NS3 POUR L'HEPATITE C
Publication
Application
Priority
- GB 9801126 W 19980416
- GB 9707659 A 19970416
Abstract (en)
[origin: WO9846630A1] Disclosed is a specific pharmacophoric profile which represents the structure for inhibitors of Hepatitis C NS3 protease. The results from mapping studies of the enzyme with depsipeptide substrates allow the generation of a particular pharmacophoric binding profile. Compounds possessing this motif were shown to be inhibitors of Hepatitis NS3 protease. The inhibitors have use in the treatment of hepatitis C.
IPC 1-7
IPC 8 full level
A61K 38/55 (2006.01); A61P 1/16 (2006.01); A61P 31/12 (2006.01); C07K 5/113 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 1/16 (2017.12); A61P 31/12 (2017.12); C07K 5/1021 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9846630A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9846630 A1 19981022; AU 7063598 A 19981111; EP 0975662 A1 20000202; GB 9707659 D0 19970604; JP 2001521516 A 20011106
DOCDB simple family (application)
GB 9801126 W 19980416; AU 7063598 A 19980416; EP 98917395 A 19980416; GB 9707659 A 19970416; JP 54364898 A 19980416