Global patent index - EP 0975662 A1

EP 0975662 A1 2000-02-02 - HEPATITIS C NS3 PROTEASE INHIBITORS

Title (en)

HEPATITIS C NS3 PROTEASE INHIBITORS

Title (de)

HEPATITIS C NS3 PROTEASE INHIBITORE

Title (fr)

INHIBITEURS DE PROTEASE NS3 POUR L'HEPATITE C

Publication

EP 0975662 A1 (EN)

Application

EP 98917395 A

Priority

  • GB 9801126 W
  • GB 9707659 A

Abstract (en)

[origin: WO9846630A1] Disclosed is a specific pharmacophoric profile which represents the structure for inhibitors of Hepatitis C NS3 protease. The results from mapping studies of the enzyme with depsipeptide substrates allow the generation of a particular pharmacophoric binding profile. Compounds possessing this motif were shown to be inhibitors of Hepatitis NS3 protease. The inhibitors have use in the treatment of hepatitis C.

IPC 1-7 (main, further and additional classification)

C07K 5/113; A61K 38/07

IPC 8 full level (invention and additional information)

A61K 38/55 (2006.01); A61P 1/16 (2006.01); A61P 31/12 (2006.01); C07K 5/113 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 5/1021 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9846630A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9846630 A1 19981022; AU 7063598 A 19981111; EP 0975662 A1 20000202; GB 9707659 D0 19970604; JP 2001521516 A 20011106

INPADOC legal status

2001-03-28 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Date of withdrawal: 20010205

2000-10-25 [RAP3] CORRECTION OF THE ADDRESS OR NAME OF APPLICANT (A DOCUMENT)

- Owner name: MEDIVIR UK LTD

- Ref Legal Event Code: RAP3

2000-09-20 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: MEDIVIR UK LTD

- Ref Legal Event Code: RAP1

2000-02-02 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991027

2000-02-02 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE