Title (en)

SCREENING FOR COMPOUNDS THAT INHIBIT PHOSPHORYLATION OF I(KAPPA)B(ALPHA)

Title (de)

SCREENING FÜR VERBINDUNGEN DIE DIE PHOSPHORYLIERUNG VON I(KAPPA)B(ALPHA) INHIBIEREN

Title (fr)

CRIBLAGE DE COMPOSES INHIBANT LA PHOSPHORYLISATION DE I(KAPPA)B(ALPHA)

Publication

EP 0975966 A1 20000202 (EN)

Application

EP 98918125 A 19980413

Priority

• US 9807330 W 19980413
• US 4382597 P 19970414

Abstract (en)

[origin: WO9846999A1] A method to identify a compound that inhibits the phosphorylation of residues serine 32 and serine 36 of I kappa B alpha by CKII is described. A method to identify a compound that selectively inhibits the up-regulation of CKII is also described.

IPC 1-7

G01N 33/53; G01N 33/573; G01N 33/574; G01N 33/567

IPC 8 full level

C12Q 1/48 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

C12Q 1/48 (2013.01); G01N 33/56988 (2013.01)

Citation (search report)

See references of WO 9846999A1

Designated contracting state (EPC)

CH DE FR GB IT LI

DOCDB simple family (publication)

WO 9846999 A1 19981022; AU 7110898 A 19981111; CA 2286073 A1 19981022; EP 0975966 A1 20000202

DOCDB simple family (application)

US 9807330 W 19980413; AU 7110898 A 19980413; CA 2286073 A 19980413; EP 98918125 A 19980413