EP 0977860 A1 20000209 - NGF VARIANTS
Title (en)
NGF VARIANTS
Title (de)
NGF VARIANTE
Title (fr)
VARIANTS DU FACTEUR DE CROISSANCE DU TISSU NERVEUX (FCN)
Publication
Application
Priority
- US 9808242 W 19980423
- US 84554197 A 19970425
- US 84104597 A 19970429
Abstract (en)
[origin: WO9849308A1] NGF variants which have trkC-binding activity and trkC-signal inducing activity are provided. The variants optionally have trkA or trkB binding and signal induction activity. The NGF variants of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the NGF variant neurotrophins are also provided.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/22 (2006.01); A61P 25/00 (2006.01); C07K 14/48 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/18 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); C07K 14/48 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9849308A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9849308 A1 19981105; AU 2002300365 A1 20030130; AU 2002300365 B2 20060713; AU 2002300365 B9 20070315; AU 7154698 A 19981124; CA 2286558 A1 19981105; EP 0977860 A1 20000209; IL 132251 A0 20010319; JP 2001527402 A 20011225
DOCDB simple family (application)
US 9808242 W 19980423; AU 2002300365 A 20020801; AU 7154698 A 19980423; CA 2286558 A 19980423; EP 98918666 A 19980423; IL 13225198 A 19980423; JP 54714498 A 19980423