Global Patent Index - EP 0977860 A1

EP 0977860 A1 2000-02-09 - NGF VARIANTS

Title (en)

NGF VARIANTS

Title (de)

NGF VARIANTE

Title (fr)

VARIANTS DU FACTEUR DE CROISSANCE DU TISSU NERVEUX (FCN)

Publication

EP 0977860 A1 (EN)

Application

EP 98918666 A

Priority

  • US 9808242 W
  • US 84554197 A
  • US 84104597 A

Abstract (en)

[origin: WO9849308A1] NGF variants which have trkC-binding activity and trkC-signal inducing activity are provided. The variants optionally have trkA or trkB binding and signal induction activity. The NGF variants of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the NGF variant neurotrophins are also provided.

IPC 1-7 (main, further and additional classification)

C12N 15/18; A61K 38/18; C07K 14/48; C12N 5/10; C12N 15/85

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/22 (2006.01); A61P 25/00 (2006.01); C07K 14/48 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/18 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)

CPC (invention and additional information)

C07K 14/48 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9849308A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9849308 A1 19981105; AU 2002300365 A1 20030130; AU 2002300365 B2 20060713; AU 2002300365 B9 20070315; AU 7154698 A 19981124; CA 2286558 A1 19981105; EP 0977860 A1 20000209; IL 132251 D0 20010319; JP 2001527402 A 20011225

INPADOC legal status


2002-09-11 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020308

2001-10-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010828

2000-02-09 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991025

2000-02-09 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE