Global Patent Index - EP 0977872 A1

EP 0977872 A1 2000-02-09 - HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Title (en)

HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Title (de)

MENSCHLICHES KOMPLEMENT C3-DEGRADIERENDE PROTEINASE AUS STREPTOCOCCUS PNEUMONIAE

Title (fr)

PROTEINASE, ISSUE DE $i(STREPTOCOCCUS PNEUMONIAE) DEGRADANT LA PROTEINE C3 HUMAINE DU COMPLEMENT

Publication

EP 0977872 A1 (EN)

Application

EP 98918689 A

Priority

  • US 9808281 W
  • US 4431697 P

Abstract (en)

[origin: WO9848022A1] The present invention relates to the identification and use of a family of human complement C3-degrading proteinases expressed by S. pneumoniae. The proteinase has a molecular weight of about 24 kD to about 34 kD as determined on a 10 % SDS polyacrylamide gel. A preferred proteinase of this invention includes the amino acid sequence of SEQ ID NO:2.

IPC 1-7 (main, further and additional classification)

C12N 15/57; A61K 38/48; C07K 16/40; C12N 1/21; C12N 5/10; C12N 9/52

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61P 37/04 (2006.01); C07K 14/315 (2006.01); C07K 16/40 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/52 (2006.01); C12N 15/57 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01); C12R 1/46 (2006.01)

CPC (invention and additional information)

C12N 9/52 (2013.01); A61K 39/00 (2013.01)

Citation (search report)

See references of WO 9848022A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9848022 A1 19981029; WO 9848022 A9 19990415; AU 7156698 A 19981113; AU 740153 B2 20011101; BR 9809405 A 20000613; CA 2283755 A1 19981029; CN 1253589 A 20000517; EP 0977872 A1 20000209; JP 2001523960 A 20011127

INPADOC legal status


2008-12-17 [18R] REFUSED

- Effective date: 20080731

2002-02-13 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020103

2000-07-26 [RTI1] TITLE (CORRECTION)

- Free text: HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM STREPTOCOCCUS PNEUMONIAE

2000-02-09 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991105

2000-02-09 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE