Global patent index - EP 0977880 A2

EP 0977880 A2 2000-02-09 - MATERIALS AND METHODS FOR TREATMENT OF RETINAL DISEASES

Title (en)

MATERIALS AND METHODS FOR TREATMENT OF RETINAL DISEASES

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON NETZHAUTERKRANKUNGEN

Title (fr)

PRODUITS AGISSANT CONTRE DES AFFECTIONS RETINIENNES ET TRAITEMENT CORRESPONDANT

Publication

EP 0977880 A2 (EN)

Application

EP 98922042 A

Priority

  • US 9808003 W
  • US 4449297 P
  • US 4614697 P

Abstract (en)

[origin: WO9848027A2] The subject invention provides materials and methods for efficient, specific expression of proteins in retinal photoreceptors cells. Specifically, the constructs are composed of an adeno-associated viral vector contacting a rod or cone-opsin promoter. These materials and methods can be used in therapies for retinal diseases. In one embodiment, ribozymes which degrade mutant mRNA are used to treat retinitis pigmentosa.

IPC 1-7 (main, further and additional classification)

C12N 15/85; A61K 31/70; A61K 48/00; C12N 9/00; C12N 15/11; C12N 15/86

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); A61P 27/02 (2006.01); C12N 9/00 (2006.01); C12N 15/113 (2010.01)

CPC (invention and additional information)

C12N 15/1136 (2013.01); C12N 15/1137 (2013.01); C12N 15/1138 (2013.01); A61K 38/00 (2013.01); C12N 2310/121 (2013.01); C12N 2310/122 (2013.01); C12N 2310/127 (2013.01); C12N 2799/025 (2013.01)

Citation (search report)

See references of WO 9848027A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9848027 A2 19981029; WO 9848027 A3 19990325; WO 9848027 A9 19990429; AU 7467598 A 19981113; BR 9809284 A 20040803; CA 2287495 A1 19981029; EP 0977880 A2 20000209; JP 2001527399 A 20011225

INPADOC legal status

2000-07-12 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Date of withdrawal: 20000216

2000-02-09 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991019

2000-02-09 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-02-09 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 19991019;LT PAYMENT 19991019;LV PAYMENT 19991019;MK PAYMENT 19991019;RO PAYMENT 19991019;SI PAYMENT 19991019