EP 0979230 A1 20000216 - 6,7-DISUBSTITUTED-4-AMINOPYRIDO¬2,3-D PYRIMIDINE COMPOUNDS
Title (en)
6,7-DISUBSTITUTED-4-AMINOPYRIDO¬2,3-D PYRIMIDINE COMPOUNDS
Title (de)
6,7-DISUBSTITUIERTE-4-AMINOPYRIDO(2,3-D)PYRIMIDINE VERBINDUNGEN
Title (fr)
COMPOSES DE 4-AMINOPYRIDO¬2,3-D PYRIMIDINE DISUBSTITUEE EN POSITION 6, 7
Publication
Application
Priority
- US 9804127 W 19980416
- US 83439397 A 19970416
Abstract (en)
[origin: WO9846603A1] A compound having formula (I), wherein R<1>, R<2>, R<3> and R<4> are defined variables selected from the groups as specified herein which include alkyl, aryl, heteroaryl and heterocyclic and substituted versions thereof, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, nociperception, pain, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods of preparation thereof.
IPC 1-7
IPC 8 full level
A61P 25/04 (2006.01); A61K 31/519 (2006.01); A61P 1/00 (2006.01); A61P 3/10 (2006.01); A61P 9/10 (2006.01); A61P 19/02 (2006.01); A61P 25/00 (2006.01); A61P 25/08 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP KR)
A61P 1/00 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 471/04 (2013.01 - EP KR)
Citation (search report)
See references of WO 9846603A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
RO SI
DOCDB simple family (publication)
WO 9846603 A1 19981022; AR 012435 A1 20001018; AU 7098198 A 19981111; AU 744528 B2 20020228; BG 103861 A 20000630; BR 9809088 A 20000801; CA 2287465 A1 19981022; CN 1259948 A 20000712; CO 4940439 A1 20000724; EP 0979230 A1 20000216; HU P0001402 A2 20001028; HU P0001402 A3 20010129; IL 131892 A0 20010319; JP 2001520649 A 20011030; KR 20010006453 A 20010126; NO 995033 D0 19991015; NO 995033 L 19991215; NZ 337844 A 20011130; PL 336262 A1 20000619; SK 142099 A3 20000516; TR 199902456 T2 20000721; TW 458977 B 20011011; ZA 982912 B 19981009
DOCDB simple family (application)
US 9804127 W 19980416; AR P980101732 A 19980415; AU 7098198 A 19980416; BG 10386199 A 19991105; BR 9809088 A 19980416; CA 2287465 A 19980416; CN 98806072 A 19980416; CO 98020309 A 19980414; EP 98917950 A 19980416; HU P0001402 A 19980416; IL 13189298 A 19980416; JP 54387898 A 19980416; KR 19997009543 A 19991015; NO 995033 A 19991015; NZ 33784498 A 19980416; PL 33626298 A 19980416; SK 142099 A 19980416; TR 9902456 T 19980416; TW 87104674 A 19980327; ZA 982912 A 19980406