EP 0979238 A1 20000216 - PROSAPTIDE 14-MER FOR USE IN THE TREATMENT OF MONONEUROPATY AND POLYNEUROPATY ASSOCIATED WITH DIABETES AND CHEMOTHERAPY
Title (en)
PROSAPTIDE 14-MER FOR USE IN THE TREATMENT OF MONONEUROPATY AND POLYNEUROPATY ASSOCIATED WITH DIABETES AND CHEMOTHERAPY
Title (de)
14-MER PROSAPTIDE ZUR VERWENDUNG BEI DER BEHANDLUNG VON MONO- UND POLYNEUROPATHIEN IN VERBINDUNG MIT DIABETES UND CHEMOTHERAPIE
Title (fr)
14-MER DU PROSAPTIDE POUR L'UTILISATION DANS LE TRAITEMENT DE LA MONONEUROPATHIE ET DE LA POLYNEUROPATHIE ASSOCIÉS AVEC LE DIABÈTE ET LA CHIMIOTHÉRAPIE
Publication
Application
Priority
- US 9716062 W 19970911
- US 9704143 W 19970305
Abstract (en)
[origin: WO9839357A1] The invention provides a method of alleviating neuropathic pain in a subject by administering a neuropathic pain alleviating amount of prosaposin receptor agonist to the subject. The invention also provides a method of inhibiting the onset of neuropathic pain in a subject by administering neuropathic pain alleviating amount of prosaposin receptor agonist to the subject. The present invention also provides prosaposin receptor agonists and the use of these agonists for stimulating neurite outgrowth, inhibiting neural cell death, promoting myelination and inhibiting neural demyelination. In addition, there is provided a method of inhibiting sensory or motor neuropathy by contacting neuronal cells with a composition comprising an effective inhibiting amount of prosaposin receptor agonist.
IPC 1-7
C07K 4/00; C07K 7/00; C07K 14/52; A61K 38/10; A61K 38/17; A61K 38/19
CPC (source: EP)
C07K 14/475 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9839357 A1 19980911; CA 2282827 A1 19980911; EP 0979238 A1 20000216; EP 0979238 A4 20000823
DOCDB simple family (application)
US 9716062 W 19970911; CA 2282827 A 19970911; EP 97941027 A 19970911