Global Patent Index - EP 0979238 A4

EP 0979238 A4 20000823 - METHOD OF ALLEVIATING NEUROPATHIC PAIN

Title (en)

METHOD OF ALLEVIATING NEUROPATHIC PAIN

Title (de)

METHODE ZUR HEILUNG NEUROPATHISCHER SCHMERZEN

Title (fr)

PROCEDES POUR SOULAGER LES DOULEURS NEUROPATHIQUES

Publication

EP 0979238 A4 20000823 (EN)

Application

EP 97941027 A 19970911

Priority

  • US 9716062 W 19970911
  • US 9704143 W 19970305

Abstract (en)

[origin: WO9839357A1] The invention provides a method of alleviating neuropathic pain in a subject by administering a neuropathic pain alleviating amount of prosaposin receptor agonist to the subject. The invention also provides a method of inhibiting the onset of neuropathic pain in a subject by administering neuropathic pain alleviating amount of prosaposin receptor agonist to the subject. The present invention also provides prosaposin receptor agonists and the use of these agonists for stimulating neurite outgrowth, inhibiting neural cell death, promoting myelination and inhibiting neural demyelination. In addition, there is provided a method of inhibiting sensory or motor neuropathy by contacting neuronal cells with a composition comprising an effective inhibiting amount of prosaposin receptor agonist.

IPC 1-7

C07K 4/00; C07K 7/00; C07K 14/52; A61K 38/10; A61K 38/17; A61K 38/19; C07K 14/475

CPC (source: EP)

C07K 14/475 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [L] WO 9732895 A1 19970912 - UNIV CALIFORNIA [US], et al
  • [L] WO 9842746 A2 19981001 - MYELOS NEUROSCIENCES CORP [US], et al
  • [A] WO 9503821 A1 19950209 - BRIEN JOHN S O [US]
  • [A] HIRAIWA, MASAO ET AL: "Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides", PROC. NATL. ACAD. SCI. U. S. A. (1997), 94(9), 4778-4781, 1997, XP002140103
  • See references of WO 9839357A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9839357 A1 19980911; CA 2282827 A1 19980911; EP 0979238 A1 20000216; EP 0979238 A4 20000823

DOCDB simple family (application)

US 9716062 W 19970911; CA 2282827 A 19970911; EP 97941027 A 19970911