Global Patent Index - EP 0979309 A1

EP 0979309 A1 2000-02-16 - OLIGONUCLEOTIDES FOR ENHANCED BIOAVAILABILITY

Title (en)

OLIGONUCLEOTIDES FOR ENHANCED BIOAVAILABILITY

Title (de)

OLIGONUKLEOTIDE MIT VERBESSERTER BIOVERFÜGBARKEIT

Title (fr)

OLIGONUCLEOTIDES PRESENTANT UNE MEILLEURE BIODISPONIBILITE

Publication

EP 0979309 A1 (EN)

Application

EP 98920076 A

Priority

  • US 9808798 W
  • US 84715197 A

Abstract (en)

[origin: WO9849348A1] The present invention provides compositions and methods for the alimentary delivery of oligonucleotides in an animal, including a human. Modifications to the oligonucleotide which enhance uptake following alimentary delivery are provided.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; A61K 48/00; C07H 21/00; C07H 21/04; C12N 5/06; C12N 15/00; C12N 15/63

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/7125 (2006.01); A61K 47/12 (2006.01); A61K 48/00 (2006.01); C07H 21/00 (2006.01); C12N 15/113 (2010.01)

CPC (invention and additional information)

C12N 15/113 (2013.01); C07H 21/00 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/346 (2013.01)

Combination set (CPC)

  1. C12N 2310/321 + C12N 2310/3527
  2. C12N 2310/321 + C12N 2310/3525
  3. C12N 2310/321 + C12N 2310/3521

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9849348 A1 19981105; AU 7272398 A 19981124; AU 738352 B2 20010913; CA 2286396 A1 19981105; CA 2286396 C 20100706; EP 0979309 A1 20000216; EP 0979309 A4 20001018; JP 2000514095 A 20001024; KR 20010020370 A 20010315

INPADOC legal status


2005-08-24 [18R] REFUSED

- Effective date: 20050401

2005-06-29 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: ISIS PHARMACEUTICALS, INC.

2003-03-12 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030124

2000-10-18 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20000830

2000-10-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-10-04 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7C 12Q 1/68 A, 7C 12N 15/00 B, 7C 12N 15/63 B, 7C 12N 5/06 B, 7C 07H 21/00 B, 7C 07H 21/04 B, 7A 61K 48/00 B, 7A 61K 31/70 B

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: DEAN, NICHOLAS, M.

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: BENNETT, C., FRANK

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: MONIA, BRETT, P.

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: DRAPER, KENNETH

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: ANDERSON, KEVIN, P.

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: BAKER, BRENDA, F.

2000-04-26 [RIN1] INVENTOR (CORRECTION)

- Inventor name: ECKER, DAVID, J.

2000-02-16 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991126

2000-02-16 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE