EP 0979309 A4 20001018 - OLIGONUCLEOTIDES FOR ENHANCED BIOAVAILABILITY
Title (en)
OLIGONUCLEOTIDES FOR ENHANCED BIOAVAILABILITY
Title (de)
OLIGONUKLEOTIDE MIT VERBESSERTER BIOVERFÜGBARKEIT
Title (fr)
OLIGONUCLEOTIDES PRESENTANT UNE MEILLEURE BIODISPONIBILITE
Publication
Application
Priority
- US 9808798 W 19980430
- US 84715197 A 19970430
Abstract (en)
[origin: WO9849348A1] The present invention provides compositions and methods for the alimentary delivery of oligonucleotides in an animal, including a human. Modifications to the oligonucleotide which enhance uptake following alimentary delivery are provided.
IPC 1-7
C12Q 1/68; C12N 15/00; C12N 15/63; C12N 5/06; C07H 21/00; C07H 21/04; A61K 48/00; A61K 31/70
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/7125 (2006.01); A61K 47/12 (2006.01); A61K 48/00 (2006.01); C07H 21/00 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP KR)
C07H 21/00 (2013.01 - EP); C12N 15/113 (2013.01 - EP); C12Q 1/68 (2013.01 - KR); C12N 2310/321 (2013.01 - EP); C12N 2310/3341 (2013.01 - EP); C12N 2310/346 (2013.01 - EP)
Citation (search report)
- [Y] WO 9612497 A1 19960502 - HYBRIDON INC [US]
- [Y] WO 9502069 A1 19950119 - ISIS PHARMACEUTICALS INC [US], et al
- [Y] EP 0626387 A1 19941130 - CIBA GEIGY AG [CH]
- [PXPY] WO 9729780 A1 19970821 - ISIS PHARMACEUTICALS INC [US], et al
- [Y] MARTIN P: "38. EIN NEUER ZUGANG ZU 2'-O-ALKYLRIBONUCLEOSIDEN UND EIGENSCHAFTEN DEREN OLIGONUCLEOTIDE", HELVETICA CHIMICA ACTA,CH,VERLAG HELVETICA CHIMICA ACTA. BASEL, vol. 78, 1995, pages 486 - 504, XP000857415, ISSN: 0018-019X
- See references of WO 9849348A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9849348 A1 19981105; AU 7272398 A 19981124; AU 738352 B2 20010913; CA 2286396 A1 19981105; CA 2286396 C 20100706; EP 0979309 A1 20000216; EP 0979309 A4 20001018; JP 2000514095 A 20001024; KR 20010020370 A 20010315
DOCDB simple family (application)
US 9808798 W 19980430; AU 7272398 A 19980430; CA 2286396 A 19980430; EP 98920076 A 19980430; JP 54741698 A 19980430; KR 19997009992 A 19991028