Global Patent Index - EP 0980244 B1

EP 0980244 B1 2003-06-04 - USE OF QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE

Title (en)

USE OF QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE

Title (de)

VERWENDUNG VON CHINAZOLIN VERBINDUNGEN ZUR BEHANDLUNG VON POLYZYSTISCHER NIERENKRANKHEIT

Title (fr)

UTILISATION DE COMPOSES DE LA QUINAZOLINE DANS LE TRAITEMENT DE LA MALADIE POLYKYSTIQUE DES REINS

Publication

EP 0980244 B1 (EN)

Application

EP 98918802 A

Priority

  • US 9808482 W
  • US 85226697 A

Abstract (en)

[origin: WO9850038A1] This invention provides a method of treating or inhibiting polycystic kidney disease in a mammal in need thereof which comprises administering to said mammal a compound having formula (1) wherein X is phenyl which is optionally substituted; R and R1 are each, independently, hydrogen, halogen, alkyl, alkoxy, hydroxy, or trifluoromethyl; R2 is hydrogen, alkyl, alkoxy, hydroxy, trifluoromethyl; Y is a radical selected from the group consisting of (a), (b), (c), (d), (e), (f) and (g); R3 is independently hydrogen, alkyl, carboxy, carboalkoxy, phenyl, or carboalkyl; n = 2-4; or a pharmaceutically acceptable salt thereof, with the proviso that each R3 of Y may be the same or different.

IPC 1-7 (main, further and additional classification)

A61K 31/505; A61P 13/12

IPC 8 full level (invention and additional information)

C07D 239/94 (2006.01); A61K 31/517 (2006.01); A61P 13/12 (2006.01); A61P 43/00 (2006.01)

CPC (invention and additional information)

A61K 31/517 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family

WO 9850038 A1 19981112; AR 012660 A1 20001108; AT 241986 T 20030615; AU 7165698 A 19981127; CA 2288705 A1 19981112; CA 2288705 C 20080318; CN 1195521 C 20050406; CN 1255062 A 20000531; DE 69815340 D1 20030710; DE 69815340 T2 20040506; DK 0980244 T3 20030929; EP 0980244 A1 20000223; EP 0980244 B1 20030604; ES 2201484 T3 20040316; HK 1025262 A1 20031017; JP 2001523267 A 20011120; JP 4327259 B2 20090909; PT 980244 E 20031031; ZA 9803731 B 19991104