Global Patent Index - EP 0980388 A1

EP 0980388 A1 2000-02-23 - VIF-DERIVED HIV PROTEASE INHIBITORS

Title (en)

VIF-DERIVED HIV PROTEASE INHIBITORS

Title (de)

VIF-DERIVATE ALS INHIBITOREN DER HIV-PROTEASE

Title (fr)

INHIBITEURS DE LA PROTEASE DU VIH DERIVANT DE LA VIF

Publication

EP 0980388 A1 (EN)

Application

EP 98924811 A

Priority

  • US 9810307 W
  • US 4720097 P

Abstract (en)

[origin: WO9852970A1] The present invention is directed to novel inhibitors of an HIV or other lentiviral or retroviral protease which are capable of inhibiting HIV or other lentiviral or retroviral replication. As such, these inhibitors are capable of reducing, eliminating or preventing viral infection. The inhibitors are peptides and polypeptides having an amino acid sequence which corresponds to the amino acid sequence of a lentiviral Vif protein (Vif-derived protease inhibitor). The invention is also directed to compositions containing the inhibitors of the invention and to methods for using such compositions in the prevention or treatment of HIV or other lentiviral and retroviral infections. The invention is also directed to methods for identifying such inhibitors in cellular model systems, HIV-infected cells, in vitro high flux assay systems, and animal model systems.

IPC 1-7 (main, further and additional classification)

C07K 14/16; A61K 38/55

IPC 8 full level (invention and additional information)

C07K 14/16 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); A61K 38/00 (2013.01); C12N 2740/16322 (2013.01)

Citation (search report)

See references of WO 9852970A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9852970 A1 19981126; WO 9852970 A9 19990325; AU 7689798 A 19981211; EP 0980388 A1 20000223; IL 132998 D0 20010319

INPADOC legal status


2004-02-25 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030819

2003-03-26 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030206

2000-02-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991220

2000-02-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE