EP 0980388 A1 20000223 - VIF-DERIVED HIV PROTEASE INHIBITORS
Title (en)
VIF-DERIVED HIV PROTEASE INHIBITORS
Title (de)
VIF-DERIVATE ALS INHIBITOREN DER HIV-PROTEASE
Title (fr)
INHIBITEURS DE LA PROTEASE DU VIH DERIVANT DE LA VIF
Publication
Application
Priority
- US 9810307 W 19980520
- US 4720097 P 19970520
Abstract (en)
[origin: WO9852970A1] The present invention is directed to novel inhibitors of an HIV or other lentiviral or retroviral protease which are capable of inhibiting HIV or other lentiviral or retroviral replication. As such, these inhibitors are capable of reducing, eliminating or preventing viral infection. The inhibitors are peptides and polypeptides having an amino acid sequence which corresponds to the amino acid sequence of a lentiviral Vif protein (Vif-derived protease inhibitor). The invention is also directed to compositions containing the inhibitors of the invention and to methods for using such compositions in the prevention or treatment of HIV or other lentiviral and retroviral infections. The invention is also directed to methods for identifying such inhibitors in cellular model systems, HIV-infected cells, in vitro high flux assay systems, and animal model systems.
IPC 1-7
IPC 8 full level
C07K 14/16 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/005 (2013.01); A61K 38/00 (2013.01); C12N 2740/16322 (2013.01)
Citation (search report)
See references of WO 9852970A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9852970 A1 19981126; WO 9852970 A9 19990325; AU 7689798 A 19981211; EP 0980388 A1 20000223; IL 132998 A0 20010319
DOCDB simple family (application)
US 9810307 W 19980520; AU 7689798 A 19980520; EP 98924811 A 19980520; IL 13299898 A 19980520