Global Patent Index - EP 0981546 A1

EP 0981546 A1 20000301 - PROTEIN SMI ON HEMATOPOIETIC STEM CELLS

Title (en)

PROTEIN SMI ON HEMATOPOIETIC STEM CELLS

Title (de)

PROTEIN SMI, DAS AN DER OBERFLÄCHE VON HÄMATOPOEITISCHEN STAMMZELLEN VORKOMMT

Title (fr)

PROTEINES SM1 PRESENTES A LA SURFACE DES CELLULES HEMATOPOIETIQUES SOUCHES

Publication

EP 0981546 A1 20000301 (EN)

Application

EP 98920093 A 19980501

Priority

  • US 9808829 W 19980501
  • US 4573097 P 19970506

Abstract (en)

[origin: WO9850429A1] A protein designated "SM1" has a molecular weight of about 230 kDa protein, as measured by immunoprecipitation and SDS-PAGE. SM1 proteins are present on the surface of human and mouse hematopoietic stem cells, respectively, and on primitive progenitor cells, but are absent from the surfaces of other cells, such as FDC-P1 myeloid progenitor cells, EL4 T-cells, WEHI-3 myelomonocytic cells, and 70Z/3 pre-B lymphoid cells, or from differentiated hematopoietic cells of human cord blood or mouse bone marrow. Anti-SM1 antibody can be employed in making a preparation that is enriched for hematopoietic stem cells.

IPC 1-7

C07K 14/705; C07K 16/28; C07H 21/04; C12Q 1/04; G01N 33/53; G01N 33/543

IPC 8 full level

C07K 14/705 (2006.01); C07K 16/28 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP)

C07K 14/705 (2013.01); C07K 16/28 (2013.01); G01N 33/56972 (2013.01); G01N 33/6872 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9850429 A1 19981112; AU 7273998 A 19981127; CA 2289727 A1 19981112; CN 1261897 A 20000802; EP 0981546 A1 20000301; EP 0981546 A4 20041124

DOCDB simple family (application)

US 9808829 W 19980501; AU 7273998 A 19980501; CA 2289727 A 19980501; CN 98806926 A 19980501; EP 98920093 A 19980501