Global Patent Index - EP 0981546 A1

EP 0981546 A1 2000-03-01 - PROTEIN SMI ON HEMATOPOIETIC STEM CELLS

Title (en)

PROTEIN SMI ON HEMATOPOIETIC STEM CELLS

Title (de)

PROTEIN SMI, DAS AN DER OBERFLÄCHE VON HÄMATOPOEITISCHEN STAMMZELLEN VORKOMMT

Title (fr)

PROTEINES SM1 PRESENTES A LA SURFACE DES CELLULES HEMATOPOIETIQUES SOUCHES

Publication

EP 0981546 A1 (EN)

Application

EP 98920093 A

Priority

  • US 9808829 W
  • US 4573097 P

Abstract (en)

[origin: WO9850429A1] A protein designated "SM1" has a molecular weight of about 230 kDa protein, as measured by immunoprecipitation and SDS-PAGE. SM1 proteins are present on the surface of human and mouse hematopoietic stem cells, respectively, and on primitive progenitor cells, but are absent from the surfaces of other cells, such as FDC-P1 myeloid progenitor cells, EL4 T-cells, WEHI-3 myelomonocytic cells, and 70Z/3 pre-B lymphoid cells, or from differentiated hematopoietic cells of human cord blood or mouse bone marrow. Anti-SM1 antibody can be employed in making a preparation that is enriched for hematopoietic stem cells.

IPC 1-7 (main, further and additional classification)

C07K 14/705; C07H 21/04; C07K 16/28; C12Q 1/04; G01N 33/53; G01N 33/543

IPC 8 full level (invention and additional information)

C07K 14/705 (2006.01); C07K 16/28 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

G01N 33/56972 (2013.01); C07K 14/705 (2013.01); C07K 16/28 (2013.01); G01N 33/6872 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9850429 A1 19981112; AU 7273998 A 19981127; CA 2289727 A1 19981112; CN 1261897 A 20000802; EP 0981546 A1 20000301; EP 0981546 A4 20041124

INPADOC legal status


2006-06-14 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20051201

2004-11-24 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20041012

2000-03-01 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991206

2000-03-01 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE