Global Patent Index - EP 0983215 A1

EP 0983215 A1 2000-03-08 - REDUCTION OF AROMATIC HALOGENIDES

Title (en)

REDUCTION OF AROMATIC HALOGENIDES

Title (de)

REDUKTION AROMATISCHER HALOGENIDE

Title (fr)

REDUCTION D'HALOGENURES AROMATIQUES

Publication

EP 0983215 A1 (DE)

Application

EP 98916623 A

Priority

  • AT 9800112 W
  • AT 86597 A

Abstract (en)

[origin: WO9852885A1] The invention relates to the reduction of (hetero)aromatic halogenides of general formula (I) Ar-Xn to compounds of general formula (II) Ar-Hn. To achieve this, a reduction agent is used, in particular a hydride reactant such as lithium aluminium hydride (LiAlH4) in the presence of oxygen, in particular in the form of an oxygen-inert gas mixture. Reduction in the presence of oxygen gives a good yield in short reaction times, even when working on a semi-industrial or industrial basis. Reduction using LiAlH4 in the presence of oxygen can also be used to reduce complicated heteroaromatic halogenides, for instance for reducing bromonarwedine ketone acetal to narwedine ketone acetal on an industrial scale.

IPC 1-7 (main, further and additional classification)

C07B 31/00; C07D 223/00; C07D 307/00; C07D 491/10

IPC 8 full level (invention and additional information)

C07D 491/06 (2006.01); C07B 31/00 (2006.01); C07C 1/26 (2006.01); C07C 15/24 (2006.01); C07D 333/10 (2006.01); C07D 491/20 (2006.01)

CPC (invention and additional information)

C07D 333/10 (2013.01); C07B 31/00 (2013.01); C07C 1/26 (2013.01)

Combination set (CPC)

C07C 1/26 + C07C 15/24

Citation (search report)

See references of WO 9852885A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9852885 A1 19981126; AT 405051 B 19990525; AT A86597 A 19980915; AU 7012798 A 19981211; BG 103880 A 20000630; BR 9809661 A 20000711; CA 2289992 A1 19981126; CN 1257467 A 20000621; EP 0983215 A1 20000308; HU 0004681 A2 20010428; JP 2001525828 A 20011211; NO 995494 A 19991110; NO 995494 D0 19991110; NZ 500733 A 20010330; PL 336906 A1 20000717; SK 158399 A3 20000711

INPADOC legal status


2002-06-19 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20011201

2000-03-08 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991008

2000-03-08 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-03-08 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 19991008;LT PAYMENT 19991008;LV PAYMENT 19991008;RO PAYMENT 19991008;SI PAYMENT 19991008