EP 0983382 A1 20000308 - ESTROGEN AND THE MENTAL STATE: MOLECULAR VARIATIONS WITHIN THE ESTROGEN RECEPTOR GENE MODULATE CLINICAL SUSCEPTIBILITY TO DEPRESSION
Title (en)
ESTROGEN AND THE MENTAL STATE: MOLECULAR VARIATIONS WITHIN THE ESTROGEN RECEPTOR GENE MODULATE CLINICAL SUSCEPTIBILITY TO DEPRESSION
Title (de)
ÖSTROGEN UND DIE MENTALE GESUNDHEIT: MOLEKULARE VERÄNDERUNGEN IM ÖSTROGEN REZEPTORGEN STEUERN DIE EMPFINDLICHKEIT FÜR KLINISCHE DEPRESSIONEN
Title (fr)
OESTROGENES ET ETAT MENTAL: VARIATIONS MOLECULAIRES DU RECEPTEUR DE L'OESTROGENE MODULATRICES DE LA SUSCEPTIBILITE A LA DEPRESSION
Publication
Application
Priority
- US 9805789 W 19980323
- US 4144997 P 19970324
Abstract (en)
[origin: WO9842872A1] The application provides evidence that genetic variations in the human estrogen receptor gene (ESR) correlate with depression. The invention provides methods of diagnosing depression or susceptibility thereto by detecting variations in the human estrogen receptor gene. The invention also provides methods of treating depression by administering an agonist of estrogen binding to the estrogen receptor.
IPC 1-7
C12Q 1/68; C07H 21/04; G01N 33/53; A61K 48/00; A61K 31/56; C07K 16/28
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6883 (2018.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)
CPC (source: EP)
C12Q 1/6883 (2013.01); G01N 33/6896 (2013.01); G01N 33/743 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/304 (2013.01)
Citation (search report)
See references of WO 9842872A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9842872 A1 19981001; AU 6771598 A 19981020; EP 0983382 A1 20000308
DOCDB simple family (application)
US 9805789 W 19980323; AU 6771598 A 19980323; EP 98913083 A 19980323