Global Patent Index - EP 0983382 A1

EP 0983382 A1 2000-03-08 - ESTROGEN AND THE MENTAL STATE: MOLECULAR VARIATIONS WITHIN THE ESTROGEN RECEPTOR GENE MODULATE CLINICAL SUSCEPTIBILITY TO DEPRESSION

Title (en)

ESTROGEN AND THE MENTAL STATE: MOLECULAR VARIATIONS WITHIN THE ESTROGEN RECEPTOR GENE MODULATE CLINICAL SUSCEPTIBILITY TO DEPRESSION

Title (de)

ÖSTROGEN UND DIE MENTALE GESUNDHEIT: MOLEKULARE VERÄNDERUNGEN IM ÖSTROGEN REZEPTORGEN STEUERN DIE EMPFINDLICHKEIT FÜR KLINISCHE DEPRESSIONEN

Title (fr)

OESTROGENES ET ETAT MENTAL: VARIATIONS MOLECULAIRES DU RECEPTEUR DE L'OESTROGENE MODULATRICES DE LA SUSCEPTIBILITE A LA DEPRESSION

Publication

EP 0983382 A1 (EN)

Application

EP 98913083 A

Priority

  • US 9805789 W
  • US 4144997 P

Abstract (en)

[origin: WO9842872A1] The application provides evidence that genetic variations in the human estrogen receptor gene (ESR) correlate with depression. The invention provides methods of diagnosing depression or susceptibility thereto by detecting variations in the human estrogen receptor gene. The invention also provides methods of treating depression by administering an agonist of estrogen binding to the estrogen receptor.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; A61K 31/56; A61K 48/00; C07H 21/04; C07K 16/28; G01N 33/53

IPC 8 full level (invention and additional information)

C12Q 1/68 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01)

CPC (invention and additional information)

C12Q 1/6883 (2013.01); G01N 33/6896 (2013.01); G01N 33/743 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/304 (2013.01)

Citation (search report)

See references of WO 9842872A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9842872 A1 19981001; AU 6771598 A 19981020; EP 0983382 A1 20000308

INPADOC legal status


2002-05-15 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20011002

2000-03-08 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991011

2000-03-08 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE