Global Patent Index - EP 0984935 A1

EP 0984935 A1 2000-03-15 - METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES

Title (en)

METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES

Title (de)

VERFAHREN ZUR HERSTELLUNG SUBSTITUIERTER THIOPYRIDINE

Title (fr)

PROCEDE DE FABRICATION DE THIOPYRIDINES SUBSTITUEES

Publication

EP 0984935 A1 (DE)

Application

EP 98929326 A

Priority

  • DE 19722661 A
  • EP 9802879 W

Abstract (en)

[origin: WO9854139A1] The invention relates to a method for producing thiopyridines of general formula (I), wherein the substituents can have the meaning cited in the description. The inventive method is characterized in that substituted 2-halogen pyridines of formula (II), wherein Hal stands for fluorine, chlorine or bromine, are reacted in a first step with a thio compound of formula (III) HS-R<5> in the presence of a copper catalyst to obtain a pyridine thioether of formula (Ia) which is then gradually oxidized to form sulphoxide (Ib) or sulphone (Ic).

IPC 1-7 (main, further and additional classification)

C07D 213/70; A01N 43/40; C07B 45/04; C07B 45/06; C07D 213/71

IPC 8 full level (invention and additional information)

C07B 45/06 (2006.01); C07D 213/70 (2006.01); C07D 213/71 (2006.01)

CPC (invention and additional information)

C07D 213/70 (2013.01); C07B 45/06 (2013.01); C07D 213/71 (2013.01)

Citation (search report)

See references of WO 9854139A1

Designated contracting state (EPC)

CH DE FR GB LI NL

EPO simple patent family

WO 9854139 A1 19981203; EP 0984935 A1 20000315; JP 2002507197 A 20020305; US 6191280 B1 20010220

INPADOC legal status


2003-10-08 [18W] WITHDRAWN

- Effective date: 20030813

2000-03-15 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991110

2000-03-15 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): CH DE FR GB LI NL