Global patent index - EP 0986538 A1

EP 0986538 A1 2000-03-22 - METHOD FOR PRODUCING CHIRAL 3,4-DEHYDROPROLINES

Title (en)

METHOD FOR PRODUCING CHIRAL 3,4-DEHYDROPROLINES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON CHIRALEN 3,4-DEHYDROPROLINEN

Title (fr)

PROCEDE DE FABRICATION DE 3,4-DEHYDROPROLINES CHIRALES

Publication

EP 0986538 A1 (DE)

Application

EP 98933585 A

Priority

  • DE 19723473 A
  • EP 9803284 W

Abstract (en)

[origin: DE19723473A1] The invention relates to a method for producing chiral 3,4-dehydroprolines of formula (I), in which R, R' and R'' have the meanings given in the description. The invention is characterized in that a pyrrolecarboxylic acid derivative of formula (II) is reacted first with an alkali or alkaline earth metal in ammonia and then with an aqueous salt solution or a compound having formula (III), in which X is a leaving group.

IPC 1-7 (main, further and additional classification)

C07D 207/20; C07D 417/12

IPC 8 full level (invention and additional information)

C07D 405/12 (2006.01); C07D 207/20 (2006.01); C07D 207/22 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01)

CPC (invention and additional information)

C07D 417/12 (2013.01); C07D 207/22 (2013.01)

Citation (search report)

See references of WO 9855456A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

DE 19723473 A1 19981210; AU 8335298 A 19981221; BR 9809726 A 20000711; CA 2291787 A1 19981210; CN 1259122 A 20000705; EP 0986538 A1 20000322; HU 0002772 A2 20001228; HU 0002772 A3 20010228; IL 132988 D0 20010319; JP 2002506430 A 20020226; KR 20010013342 A 20010226; MX 9910984 A 20000401; NO 995939 A 19991203; NO 995939 D0 19991203; US 6166222 A 20001226; WO 9855456 A1 19981210; ZA 9804814 B 19991217

INPADOC legal status

2004-03-17 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030916

2003-05-07 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: ABBOTT GMBH & CO. KG

- Ref Legal Event Code: RAP1

2000-03-22 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991116

2000-03-22 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-03-22 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: RO PAYMENT 19991116;SI PAYMENT 19991116