Global Patent Index - EP 0986553 A1

EP 0986553 A1 2000-03-22 - DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS

Title (en)

DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS

Title (de)

DIHYDROPYRIMIDON-DERIVATE ALS NPY-ANTAGONISTEN

Title (fr)

DERIVES DE DIHYDROPYRIMIDONE COMME ANTAGONISTES DU NEUROPEPTIDE Y (NPY)

Publication

EP 0986553 A1 (EN)

Application

EP 98902841 A

Priority

  • US 9801429 W
  • US 3718397 P
  • US 5089397 P

Abstract (en)

[origin: WO9833791A1] The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of formula (I), wherein R, R<1> and R<2> are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

IPC 1-7 (main, further and additional classification)

C07D 401/12; A61K 31/505

IPC 8 full level (invention and additional information)

A61K 31/513 (2006.01); A61P 3/04 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01)

CPC (invention and additional information)

C07D 401/12 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9833791 A1 19980806; AU 5963998 A 19980825; AU 733883 B2 20010531; CA 2277965 A1 19980806; EP 0986553 A1 20000322; EP 0986553 A4 20001227; JP 2002514199 A 20020514

INPADOC legal status


2002-05-22 [18R] REFUSED

- Effective date: 20011222

2001-04-18 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010301

2000-12-27 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20001110

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-03-22 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990906

2000-03-22 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE