EP 0986553 A1 20000322 - DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS
Title (en)
DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS
Title (de)
DIHYDROPYRIMIDON-DERIVATE ALS NPY-ANTAGONISTEN
Title (fr)
DERIVES DE DIHYDROPYRIMIDONE COMME ANTAGONISTES DU NEUROPEPTIDE Y (NPY)
Publication
Application
Priority
- US 9801429 W 19980126
- US 3718397 P 19970204
- US 5089397 P 19970626
Abstract (en)
[origin: WO9833791A1] The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of formula (I), wherein R, R<1> and R<2> are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
IPC 1-7
IPC 8 full level
A61K 31/513 (2006.01); A61P 3/04 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01)
CPC (source: EP)
A61P 3/04 (2017.12); A61P 43/00 (2017.12); C07D 401/12 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9833791 A1 19980806; AU 5963998 A 19980825; AU 733883 B2 20010531; CA 2277965 A1 19980806; EP 0986553 A1 20000322; EP 0986553 A4 20001227; JP 2002514199 A 20020514
DOCDB simple family (application)
US 9801429 W 19980126; AU 5963998 A 19980126; CA 2277965 A 19980126; EP 98902841 A 19980126; JP 53298398 A 19980126