Global Patent Index - EP 0986553 A4

EP 0986553 A4 2000-12-27 - DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS

Title (en)

DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS

Title (de)

DIHYDROPYRIMIDON-DERIVATE ALS NPY-ANTAGONISTEN

Title (fr)

DERIVES DE DIHYDROPYRIMIDONE COMME ANTAGONISTES DU NEUROPEPTIDE Y (NPY)

Publication

EP 0986553 A4 (EN)

Application

EP 98902841 A

Priority

  • US 9801429 W
  • US 3718397 P
  • US 5089397 P

Abstract (en)

[origin: WO9833791A1] The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of formula (I), wherein R, R<1> and R<2> are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

IPC 1-7 (main, further and additional classification)

C07D 401/12; A61K 31/505

IPC 8 full level (invention and additional information)

A61K 31/513 (2006.01); A61P 3/04 (2006.01); A61P 43/00 (2006.01); C07D 401/12 (2006.01)

CPC (invention and additional information)

C07D 401/12 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9833791 A1 19980806; AU 5963998 A 19980825; AU 733883 B2 20010531; CA 2277965 A1 19980806; EP 0986553 A1 20000322; EP 0986553 A4 20001227; JP 2002514199 A 20020514

INPADOC legal status


2002-05-22 [18R] REFUSED

- Effective date: 20011222

2001-04-18 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010301

2000-12-27 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20001110

2000-12-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-03-22 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990906

2000-03-22 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE