Global patent index - EP 0988030 A1

EP 0988030 A1 2000-03-29 - KNOBBY NANOSPHERES

Title (en)

KNOBBY NANOSPHERES

Title (de)

KNOBBY NANOSPHÄREN

Title (fr)

NANOSPHERES A KNOB

Publication

EP 0988030 A1 (EN)

Application

EP 98926552 A

Priority

  • US 9812126 W
  • US 4949697 P

Abstract (en)

[origin: WO9856363A1] The isolation and purification of adenovirus fiber protein Knob domain is taught, as well as its use as a ligand for intracellular delivery of bioactive agents, such as low molecular drugs, proteins, antisense oligonucleotides, and plasmid DNAs. The conjugation of Knob to the surface of DNA-nanospheres facilitates the binding of nanospheres to cell surfaces and enhances transfection efficiency of DNA-nanospheres.

IPC 1-7 (main, further and additional classification)

A61K 9/51; A61K 47/48

IPC 8 full level (invention and additional information)

A61K 9/51 (2006.01); A61K 47/48 (2006.01)

CPC (invention and additional information)

A61K 9/5161 (2013.01); A61K 47/48238 (2013.01); A61K 47/48923 (2013.01); B82Y 5/00 (2013.01)

Citation (search report)

See references of WO 9856363A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9856363 A1 19981217; AU 7836598 A 19981230; EP 0988030 A1 20000329

INPADOC legal status

2005-07-06 [18R] REFUSED

- Ref Legal Event Code: 18R

- Effective date: 20050219

2003-12-10 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20031027

2000-11-29 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: THE JOHNS HOPKINS UNIVERSITY

- Ref Legal Event Code: RAP1

2000-03-29 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000112

2000-03-29 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE