EP 0988030 A1 20000329 - KNOBBY NANOSPHERES
Title (en)
KNOBBY NANOSPHERES
Title (de)
KNOBBY NANOSPHÄREN
Title (fr)
NANOSPHERES A KNOB
Publication
Application
Priority
- US 9812126 W 19980611
- US 4949697 P 19970613
Abstract (en)
[origin: WO9856363A1] The isolation and purification of adenovirus fiber protein Knob domain is taught, as well as its use as a ligand for intracellular delivery of bioactive agents, such as low molecular drugs, proteins, antisense oligonucleotides, and plasmid DNAs. The conjugation of Knob to the surface of DNA-nanospheres facilitates the binding of nanospheres to cell surfaces and enhances transfection efficiency of DNA-nanospheres.
IPC 1-7
IPC 8 full level
A61K 9/51 (2006.01); A61K 47/48 (2006.01)
CPC (source: EP)
A61K 9/5161 (2013.01); A61K 47/62 (2017.07); A61K 47/6939 (2017.07); B82Y 5/00 (2013.01)
Citation (search report)
See references of WO 9856363A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9856363 A1 19981217; AU 7836598 A 19981230; EP 0988030 A1 20000329
DOCDB simple family (application)
US 9812126 W 19980611; AU 7836598 A 19980611; EP 98926552 A 19980611