Global Patent Index - EP 0988030 A1

EP 0988030 A1 20000329 - KNOBBY NANOSPHERES

Title (en)

KNOBBY NANOSPHERES

Title (de)

KNOBBY NANOSPHÄREN

Title (fr)

NANOSPHERES A KNOB

Publication

EP 0988030 A1 (EN)

Application

EP 98926552 A

Priority

  • US 9812126 W
  • US 4949697 P

Abstract (en)

[origin: WO9856363A1] The isolation and purification of adenovirus fiber protein Knob domain is taught, as well as its use as a ligand for intracellular delivery of bioactive agents, such as low molecular drugs, proteins, antisense oligonucleotides, and plasmid DNAs. The conjugation of Knob to the surface of DNA-nanospheres facilitates the binding of nanospheres to cell surfaces and enhances transfection efficiency of DNA-nanospheres.

IPC 1-7

A61K 9/51; A61K 47/48

IPC 8 full level

A61K 9/51 (2006.01); A61K 47/48 (2006.01)

CPC (source: EP)

A61K 9/5161 (2013.01); A61K 47/62 (2017.08); A61K 47/6939 (2017.08); B82Y 5/00 (2013.01)

Citation (search report)

See references of WO 9856363A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9856363 A1 19981217; AU 7836598 A 19981230; EP 0988030 A1 20000329

DOCDB simple family (application)

US 9812126 W 19980611; AU 7836598 A 19980611; EP 98926552 A 19980611