Global Patent Index - EP 0989984 A1

EP 0989984 A1 20000405 - BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (en)

BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (de)

BISPYRIDO-CYCLOHEPTAN DERIVATE MIT FARNESYL PROTEIN TRANSFERASE INHIBIERENDER WIRKUNG

Title (fr)

COMPOSES DE BISPYRIDO-CYCLOHEPTANE UTILES POUR L'INHIBITION DE FARNESYL PROTEINE TRANSFERASE

Publication

EP 0989984 A1 20000405 (EN)

Application

EP 98928887 A 19980615

Priority

  • US 9811496 W 19980615
  • US 87774397 A 19970617

Abstract (en)

[origin: WO9857961A1] Novel compounds of formula (1.0) or (2.0) are disclosed. Also disclosed is a method of inhibiting farnesyl protein transferase function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of said formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Also disclosed is a method of effecting an anti-allergic response by administering the compounds.

IPC 1-7

C07D 401/14; A61K 31/55; C07D 401/04; A61K 31/495; A61K 31/44

IPC 8 full level

A61K 31/4545 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 471/04 (2006.01)

CPC (source: EP KR)

A61P 35/00 (2018.01 - EP); A61P 37/08 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 401/14 (2013.01 - KR); C07D 471/04 (2013.01 - EP)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9857961 A1 19981223; AR 015122 A1 20010418; AU 744153 B2 20020214; AU 8058198 A 19990104; CA 2293713 A1 19981223; CA 2293713 C 20061205; CN 1266432 A 20000913; CO 4940447 A1 20000724; EP 0989984 A1 20000405; HU P0004274 A2 20010828; HU P0004274 A3 20020328; IL 133388 A0 20010430; JP 2002504145 A 20020205; KR 20010013825 A 20010226; NZ 501418 A 20010427; ZA 985214 B 19990107

DOCDB simple family (application)

US 9811496 W 19980615; AR P980102863 A 19980616; AU 8058198 A 19980615; CA 2293713 A 19980615; CN 98808118 A 19980615; CO 98034143 A 19980616; EP 98928887 A 19980615; HU P0004274 A 19980615; IL 13338898 A 19980615; JP 50449199 A 19980615; KR 19997011845 A 19991215; NZ 50141898 A 19980615; ZA 985214 A 19980615