Global Patent Index - EP 0989984 A1

EP 0989984 A1 2000-04-05 - BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (en)

BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (de)

BISPYRIDO-CYCLOHEPTAN DERIVATE MIT FARNESYL PROTEIN TRANSFERASE INHIBIERENDER WIRKUNG

Title (fr)

COMPOSES DE BISPYRIDO-CYCLOHEPTANE UTILES POUR L'INHIBITION DE FARNESYL PROTEINE TRANSFERASE

Publication

EP 0989984 A1 (EN)

Application

EP 98928887 A

Priority

  • US 9811496 W
  • US 87774397 A

Abstract (en)

[origin: WO9857961A1] Novel compounds of formula (1.0) or (2.0) are disclosed. Also disclosed is a method of inhibiting farnesyl protein transferase function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of said formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Also disclosed is a method of effecting an anti-allergic response by administering the compounds.

IPC 1-7 (main, further and additional classification)

C07D 401/14; A61K 31/44; A61K 31/495; A61K 31/55; C07D 401/04

IPC 8 full level (invention and additional information)

A61K 31/4545 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 471/04 (2006.01)

CPC (invention and additional information)

C07D 471/04 (2013.01)

Citation (search report)

See references of WO 9857961A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9857961 A1 19981223; AR 015122 A1 20010418; AU 744153 B2 20020214; AU 8058198 A 19990104; CA 2293713 A1 19981223; CA 2293713 C 20061205; CN 1266432 A 20000913; CO 4940447 A1 20000724; EP 0989984 A1 20000405; HU 0004274 A2 20010828; HU 0004274 A3 20020328; IL 133388 D0 20010430; JP 2002504145 A 20020205; KR 20010013825 A 20010226; NZ 501418 A 20010427; ZA 9805214 B 19990107

INPADOC legal status


2007-04-25 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20061007

2007-01-19 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1023115

2003-03-26 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030211

2000-04-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991227

2000-04-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-04-05 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: LT PAYMENT 19991227;LV PAYMENT 19991227;RO PAYMENT 19991227