Global Patent Index - EP 0989984 A1

EP 0989984 A1 20000405 - BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (en)

BISPYRIDO-CYCLOHEPTANE COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE

Title (de)

BISPYRIDO-CYCLOHEPTAN DERIVATE MIT FARNESYL PROTEIN TRANSFERASE INHIBIERENDER WIRKUNG

Title (fr)

COMPOSES DE BISPYRIDO-CYCLOHEPTANE UTILES POUR L'INHIBITION DE FARNESYL PROTEINE TRANSFERASE

Publication

EP 0989984 A1 20000405 (EN)

Application

EP 98928887 A 19980615

Priority

  • US 9811496 W 19980615
  • US 87774397 A 19970617

Abstract (en)

[origin: WO9857961A1] Novel compounds of formula (1.0) or (2.0) are disclosed. Also disclosed is a method of inhibiting farnesyl protein transferase function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of said formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Also disclosed is a method of effecting an anti-allergic response by administering the compounds.

IPC 1-7

C07D 401/14; A61K 31/55; C07D 401/04; A61K 31/495; A61K 31/44

IPC 8 full level

A61K 31/4545 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 471/04 (2006.01)

CPC (source: EP KR)

A61P 35/00 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 401/14 (2013.01 - KR); C07D 471/04 (2013.01 - EP)

Citation (search report)

See references of WO 9857961A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9857961 A1 19981223; AR 015122 A1 20010418; AU 744153 B2 20020214; AU 8058198 A 19990104; CA 2293713 A1 19981223; CA 2293713 C 20061205; CN 1266432 A 20000913; CO 4940447 A1 20000724; EP 0989984 A1 20000405; HU P0004274 A2 20010828; HU P0004274 A3 20020328; IL 133388 A0 20010430; JP 2002504145 A 20020205; KR 20010013825 A 20010226; NZ 501418 A 20010427; ZA 985214 B 19990107

DOCDB simple family (application)

US 9811496 W 19980615; AR P980102863 A 19980616; AU 8058198 A 19980615; CA 2293713 A 19980615; CN 98808118 A 19980615; CO 98034143 A 19980616; EP 98928887 A 19980615; HU P0004274 A 19980615; IL 13338898 A 19980615; JP 50449199 A 19980615; KR 19997011845 A 19991215; NZ 50141898 A 19980615; ZA 985214 A 19980615