Global Patent Index - EP 0989998 A1

EP 0989998 A1 2000-04-05 - IMPROVED BACILLUS THURINGIENSIS TOXIN

Title (en)

IMPROVED BACILLUS THURINGIENSIS TOXIN

Title (de)

VERBESSERTES BACILLUS THURINGIENSIS-TOXINS

Title (fr)

TOXINE DE BACILLUS THURINGIENSIS AMELIOREE

Publication

EP 0989998 A1 (EN)

Application

EP 98939581 A

Priority

  • EP 9804033 W
  • US 88438997 A

Abstract (en)

[origin: WO9900407A2] New improved Cry9C proteins, having significantly increased toxicity, and DNA sequences encoding these proteins, were designed. Analysis of amino acid positions in domain II of the Cry9C protein by protein mutagenesis identified amino acids involved in insect toxicity. Random replacement of these amino acids identifies proteins with improved toxicity. A combination of identified improved amino acids in a single protein yields modified Cry9C proteins with significantly improved toxicity.

IPC 1-7 (main, further and additional classification)

C07K 14/00

IPC 8 full level (invention and additional information)

C07K 14/325 (2006.01); C12N 15/82 (2006.01)

CPC (invention and additional information)

C12N 15/8286 (2013.01); C07K 14/325 (2013.01)

Citation (search report)

See references of WO 9900407A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9900407 A2 19990107; WO 9900407 A3 19990514; AU 741600 B2 20011206; AU 8804498 A 19990119; CA 2290718 A1 19990107; EP 0989998 A1 20000405

INPADOC legal status


2003-07-02 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030103

2000-04-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000118

2000-04-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE