Global Patent Index - EP 0991774 A1

EP 0991774 A1 2000-04-12 - METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS

Title (en)

METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS

Title (de)

VERFAHREN ZUR ERHÖHUNG DER PROTEINSEKRETION IN EUKARYOTISCHEN WIRTSZELLEN

Title (fr)

PROCEDE SERVANT A AUGMENTER LA SECRETION DE PROTEINES DANS DES CELLULES HOTES EUCARYOTES

Publication

EP 0991774 A1 (EN)

Application

EP 98933141 A

Priority

  • US 9813870 W
  • US 5172197 P

Abstract (en)

[origin: WO9901565A1] A method is provided whereby genetically altered cells exhibit increased levels of secreted protein, such as to provide increased yields of recombinant proteins. The cells are genetically altered to increase synthesis of ribosome receptors, which induces proliferation of components of the secretory pathway.

IPC 1-7 (main, further and additional classification)

C12P 21/06; C07K 14/47; C07K 14/705; C12N 5/00; C12N 5/02; C12N 5/06; C12N 5/10; C12N 15/00; C12N 15/81; C12N 15/85; C12P 21/02

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 5/10 (2006.01); C12N 15/67 (2006.01); C12N 15/81 (2006.01); C12N 15/85 (2006.01); C12P 21/02 (2006.01)

CPC (invention and additional information)

C12P 21/02 (2013.01); C07K 14/47 (2013.01); C07K 14/705 (2013.01); C12N 15/67 (2013.01); C12N 15/81 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9901565 A1 19990114; WO 9901565 A9 19990422; AU 744484 B2 20020228; AU 8287398 A 19990125; CA 2295310 A1 19990114; EP 0991774 A1 20000412; EP 0991774 A4 20050406; JP 2002507894 A 20020312

INPADOC legal status


2007-10-17 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20070315

2006-10-04 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20050719

2005-04-06 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20050221

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12P 21/06 A

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/00 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/02 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/06 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 5/10 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/00 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12P 21/02 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/81 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12N 15/85 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07K 14/47 B

2005-04-06 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 07K 14/705 B

2000-04-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000126

2000-04-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE