EP 0991774 A4 20050406 - METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS
Title (en)
METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS
Title (de)
VERFAHREN ZUR ERHÖHUNG DER PROTEINSEKRETION IN EUKARYOTISCHEN WIRTSZELLEN
Title (fr)
PROCEDE SERVANT A AUGMENTER LA SECRETION DE PROTEINES DANS DES CELLULES HOTES EUCARYOTES
Publication
Application
Priority
- US 9813870 W 19980702
- US 5172197 P 19970703
Abstract (en)
[origin: WO9901565A1] A method is provided whereby genetically altered cells exhibit increased levels of secreted protein, such as to provide increased yields of recombinant proteins. The cells are genetically altered to increase synthesis of ribosome receptors, which induces proliferation of components of the secretory pathway.
IPC 1-7
C12P 21/06; C12N 5/00; C12N 5/02; C12N 5/06; C12N 5/10; C12N 15/00; C12P 21/02; C12N 15/81; C12N 15/85; C07K 14/47; C07K 14/705
IPC 8 full level
C12N 15/09 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 5/10 (2006.01); C12N 15/67 (2006.01); C12N 15/81 (2006.01); C12N 15/85 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C07K 14/705 (2013.01); C12N 15/67 (2013.01); C12N 15/81 (2013.01); C12P 21/02 (2013.01)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 9901565A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9901565 A1 19990114; WO 9901565 A9 19990422; AU 744484 B2 20020228; AU 8287398 A 19990125; CA 2295310 A1 19990114; EP 0991774 A1 20000412; EP 0991774 A4 20050406; JP 2002507894 A 20020312
DOCDB simple family (application)
US 9813870 W 19980702; AU 8287398 A 19980702; CA 2295310 A 19980702; EP 98933141 A 19980702; JP 50742799 A 19980702