Global Patent Index - EP 0991793 A1

EP 0991793 A1 20000412 - METHOD FOR PREPARING 2-ARYL OR 2-HETEROCYCLYL CHIRAL PROPIONIC ACIDS AND THEIR ESTERS

Title (en)

METHOD FOR PREPARING 2-ARYL OR 2-HETEROCYCLYL CHIRAL PROPIONIC ACIDS AND THEIR ESTERS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON CHIRALEN 2-ARYL ODER 2-HETEROCYCLYL PROPIONSÄUREN UND DEREN ESTER

Title (fr)

PROCEDE DE PREPARATION D'ACIDES 2-ARYL OU 2-HETEROCYCLYL PROPIONIQUES CHIRAUX ET LEURS ESTERS

Publication

EP 0991793 A1 20000412 (FR)

Application

EP 98933708 A 19980624

Priority

  • FR 9801336 W 19980624
  • FR 9707908 A 19970625

Abstract (en)

[origin: FR2765246A1] The invention concerns a method for preparing 2-aryl or 2-heterocyclyl chiral propionic acids and their esters by electrochemical reduction of a mixture of a propionic acid derivative of formula (II) in which R3 represents a radical of formula (A), (B), (C) and Hal represents a halogen atom and an aromatic or heterocyclic halogen derivative, in the presence of a nickel complex as catalyst and an electrolyte, then either by hydrolysis to obtain the propionic acid derivative or by transesterification to obtain the ester.

IPC 1-7

C25B 3/04

IPC 8 full level

C07D 233/14 (2006.01); C07B 37/04 (2006.01); C07B 41/08 (2006.01); C07C 51/09 (2006.01); C07C 57/30 (2006.01); C07C 57/38 (2006.01); C07C 59/68 (2006.01); C07C 59/84 (2006.01); C07C 67/03 (2006.01); C07C 69/612 (2006.01); C07C 69/65 (2006.01); C07C 69/734 (2006.01); C07C 69/738 (2006.01); C07C 227/10 (2006.01); C07C 229/42 (2006.01); C07D 213/55 (2006.01); C07D 263/26 (2006.01); C07D 333/24 (2006.01); C25B 3/25 (2021.01)

CPC (source: EP US)

C25B 3/25 (2021.01 - EP US)

Designated contracting state (EPC)

DE FR GB IT

DOCDB simple family (publication)

FR 2765246 A1 19981231; FR 2765246 B1 19990917; DE 69802809 D1 20020117; EP 0991793 A1 20000412; EP 0991793 B1 20011205; JP 2002507972 A 20020312; US 6294069 B1 20010925; WO 9900535 A1 19990107

DOCDB simple family (application)

FR 9707908 A 19970625; DE 69802809 T 19980624; EP 98933708 A 19980624; FR 9801336 W 19980624; JP 50532499 A 19980624; US 44649600 A 20000127