Global Patent Index - EP 0993318 A1

EP 0993318 A1 2000-04-19 - DEVICE FOR OPTIMIZED ELECTROTRANSFER OF NUCLEIC ACID VECTORS TO TISSUES IN VIVO

Title (en)

DEVICE FOR OPTIMIZED ELECTROTRANSFER OF NUCLEIC ACID VECTORS TO TISSUES IN VIVO

Title (de)

VORRICHTUNG ZUR OPTIMIERTEN ELEKTROTRANSFER DER NUKLEINSÄUREN VEKTOREN AN GEWEBE IN VIVO

Title (fr)

DISPOSITIF PERMETTANT UN TRANSFERT IN VIVO OPTIMISE DE VECTEURS D'ACIDES NUCLEIQUES DANS DES TISSUS

Publication

EP 0993318 A1 (EN)

Application

EP 98938676 A

Priority

  • EP 9803976 W
  • FR 9708233 A
  • FR 9708232 A
  • US 6748897 P
  • US 6748797 P
  • US 8385898 P

Abstract (en)

[origin: WO9901175A1] This invention is directed to systems and devices that provide for remarkable enhancement of in vivo transfer into cells, particularly muscle cells and tumor cells, of nucleic acid vectors using weak electric fields, to increase the efficiency of such transfers. The devices of the invention are designed to provide an optimum voltage gradient to enhance migration of nucleic acid vectors into cells, without damaging the cells or tissue. Such devices are characterized by unique arrangements of electrodes, and by unique power limits defined by maximum voltage settings.

IPC 1-7 (main, further and additional classification)

A61N 1/32

IPC 8 full level (invention and additional information)

A61N 1/30 (2006.01); A61K 48/00 (2006.01); A61N 1/32 (2006.01)

CPC (invention and additional information)

A61K 48/00 (2013.01); A61N 1/325 (2013.01)

Citation (search report)

See references of WO 9901175A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9901175 A1 19990114; AU 8730798 A 19990125; BR 9810500 A 20000905; CA 2295029 A1 19990114; CN 1261812 A 20000802; EP 0993318 A1 20000419; IL 133709 D0 20010430; JP 2002515816 A 20020528; KR 20010014298 A 20010226; NO 996540 A 20000203; NO 996540 D0 19991229; PL 337617 A1 20000828

INPADOC legal status


2003-03-26 [18R] REFUSED

- Effective date: 20021218

2000-10-11 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20000824

2000-04-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991227

2000-04-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-04-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: SI PAYMENT 19991227