EP 0993318 A1 20000419 - DEVICE FOR OPTIMIZED ELECTROTRANSFER OF NUCLEIC ACID VECTORS TO TISSUES IN VIVO
Title (en)
DEVICE FOR OPTIMIZED ELECTROTRANSFER OF NUCLEIC ACID VECTORS TO TISSUES IN VIVO
Title (de)
VORRICHTUNG ZUR OPTIMIERTEN ELEKTROTRANSFER DER NUKLEINSÄUREN VEKTOREN AN GEWEBE IN VIVO
Title (fr)
DISPOSITIF PERMETTANT UN TRANSFERT IN VIVO OPTIMISE DE VECTEURS D'ACIDES NUCLEIQUES DANS DES TISSUS
Publication
Application
Priority
- EP 9803976 W 19980630
- FR 9708233 A 19970630
- FR 9708232 A 19970630
- US 6748897 P 19971201
- US 6748797 P 19971201
- US 8385898 P 19980501
Abstract (en)
[origin: WO9901175A1] This invention is directed to systems and devices that provide for remarkable enhancement of in vivo transfer into cells, particularly muscle cells and tumor cells, of nucleic acid vectors using weak electric fields, to increase the efficiency of such transfers. The devices of the invention are designed to provide an optimum voltage gradient to enhance migration of nucleic acid vectors into cells, without damaging the cells or tissue. Such devices are characterized by unique arrangements of electrodes, and by unique power limits defined by maximum voltage settings.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); A61N 1/30 (2006.01); A61N 1/32 (2006.01)
CPC (source: EP KR)
A61K 48/00 (2013.01 - EP); A61N 1/32 (2013.01 - KR); A61N 1/325 (2013.01 - EP)
Citation (search report)
See references of WO 9901175A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9901175 A1 19990114; AU 8730798 A 19990125; BR 9810500 A 20000905; CA 2295029 A1 19990114; CN 1261812 A 20000802; EP 0993318 A1 20000419; IL 133709 A0 20010430; JP 2002515816 A 20020528; KR 20010014298 A 20010226; NO 996540 D0 19991229; NO 996540 L 20000203; PL 337617 A1 20000828
DOCDB simple family (application)
EP 9803976 W 19980630; AU 8730798 A 19980630; BR 9810500 A 19980630; CA 2295029 A 19980630; CN 98806793 A 19980630; EP 98938676 A 19980630; IL 13370998 A 19980630; JP 50807599 A 19980630; KR 19997012430 A 19991229; NO 996540 A 19991229; PL 33761798 A 19980630