EP 0994715 A1 20000426 - DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF
Title (en)
DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF
Title (de)
DIFLUORNUKLEOSID-PHOSPHORSÄUREN UND IHRE DERIVATE
Title (fr)
ACIDES DIFLUORONUCLEOSIDES-PHOSPHONIQUES ET LEURS DERIVES
Publication
Application
Priority
- US 9805477 W 19980319
- US 4150797 P 19970324
Abstract (en)
[origin: WO9842351A1] Difluoronucleoside phosphonic acids and derivatives thereof of formula (II) where R is base selected from the group consisting of: (i), (ii), (iii), (iv), and (v) wherein R<1> is hydrogen, methyl, bromo, fluoro, chloro or iodo; R<2> is hydroxy or -NR<4>R<5>, where R<4> and R<5> are independently selected from the group consisting of hydrogen, methyl, ethyl and propyl; R<3> is hydrogen, bromo, chloro or iodo; both R<6> are the same, and are either -OR<7> or -(O<->R<8>), where R<7> is selected from the group consisting of hydrogen, methyl, ethyl, and isopropyl; R<8> is a pharmaceutically acceptable cation; and pharmaceutically acceptable salts and solvates thereof; are described and claimed as antiviral and antineoplastic agents.
IPC 1-7
IPC 8 full level
A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); A61K 31/708 (2006.01); A61P 31/12 (2006.01); A61P 31/22 (2006.01); A61P 35/00 (2006.01); C07H 19/073 (2006.01); C07H 19/10 (2006.01); C07H 19/173 (2006.01); C07H 19/20 (2006.01)
CPC (source: EP)
A61P 31/12 (2017.12); A61P 31/22 (2017.12); A61P 35/00 (2017.12); C07H 19/10 (2013.01); C07H 19/20 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9842351 A1 19981001; AU 6473098 A 19981020; CA 2284263 A1 19981001; EP 0994715 A1 20000426; EP 0994715 A4 20010808; JP 2001518931 A 20011016
DOCDB simple family (application)
US 9805477 W 19980319; AU 6473098 A 19980319; CA 2284263 A 19980319; EP 98910503 A 19980319; JP 54582098 A 19980319