Global Patent Index - EP 0994715 A1

EP 0994715 A1 2000-04-26 - DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF

Title (en)

DIFLUORONUCLEOSIDE PHOSPHONIC ACIDS AND DERIVATIVES THEREOF

Title (de)

DIFLUORNUKLEOSID-PHOSPHORSÄUREN UND IHRE DERIVATE

Title (fr)

ACIDES DIFLUORONUCLEOSIDES-PHOSPHONIQUES ET LEURS DERIVES

Publication

EP 0994715 A1 (EN)

Application

EP 98910503 A

Priority

  • US 9805477 W
  • US 4150797 P

Abstract (en)

[origin: WO9842351A1] Difluoronucleoside phosphonic acids and derivatives thereof of formula (II) where R is base selected from the group consisting of: (i), (ii), (iii), (iv), and (v) wherein R<1> is hydrogen, methyl, bromo, fluoro, chloro or iodo; R<2> is hydroxy or -NR<4>R<5>, where R<4> and R<5> are independently selected from the group consisting of hydrogen, methyl, ethyl and propyl; R<3> is hydrogen, bromo, chloro or iodo; both R<6> are the same, and are either -OR<7> or -(O<->R<8>), where R<7> is selected from the group consisting of hydrogen, methyl, ethyl, and isopropyl; R<8> is a pharmaceutically acceptable cation; and pharmaceutically acceptable salts and solvates thereof; are described and claimed as antiviral and antineoplastic agents.

IPC 1-7 (main, further and additional classification)

A61K 31/70; C07H 19/00

IPC 8 full level (invention and additional information)

C07H 19/073 (2006.01); A61K 31/7068 (2006.01); A61K 31/7072 (2006.01); A61K 31/7076 (2006.01); A61K 31/708 (2006.01); A61P 31/12 (2006.01); A61P 31/22 (2006.01); A61P 35/00 (2006.01); C07H 19/10 (2006.01); C07H 19/173 (2006.01); C07H 19/20 (2006.01)

CPC (invention and additional information)

C07H 19/10 (2013.01); C07H 19/20 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

EPO simple patent family

WO 9842351 A1 19981001; AU 6473098 A 19981020; CA 2284263 A1 19981001; EP 0994715 A1 20000426; EP 0994715 A4 20010808; JP 2001518931 A 20011016

INPADOC legal status


2002-04-10 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20010911

2001-08-08 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20010622

2001-08-08 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

2001-08-01 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7A 61K 31/70 A, 7C 07H 19/10 B, 7C 07H 19/20 B

2000-04-26 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990922

2000-04-26 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE