Global patent index - EP 0994717 A1

EP 0994717 A1 2000-04-26 - TREATMENT OF AUTOIMMUNE DISEASE USING TOLERIZATION IN COMBINATION WITH METHOTREXATE

Title (en)

TREATMENT OF AUTOIMMUNE DISEASE USING TOLERIZATION IN COMBINATION WITH METHOTREXATE

Title (de)

BEHANDLUNG VON AUTOIMMUNERKRANKUNGEN ANHAND EINER TOLERANZERHOEHUNG BEWIRKT DURCH DIE KOMBINATION MIT METHOTREXAT

Title (fr)

TRAITEMENT DES MALADIES AUTO-IMMUNES A L'AIDE D'UNE TOLERANCE INDUITE EN COMBINAISON AVEC DU METHOTREXATE

Publication

EP 0994717 A1 (EN)

Application

EP 98908452 A

Priority

  • US 9801648 W
  • US 3672297 P

Abstract (en)

[origin: WO9832451A1] A combination of a mucosally administrable bystander antigen and an orally, enterally, or parenterally administrable methotrexate is employed to make a pharmaceutical formulation and to treat or prevent autoimmune disease. The amounts of bystander antigen and methotrexate are effective in combination to suppress autoimmune response associated with the autoimmune disease.

IPC 1-7 (main, further and additional classification)

A61K 35/30; A61K 31/495; A61K 31/50; A61K 38/00; A61K 38/28

IPC 8 full level (invention and additional information)

C07D 475/08 (2006.01); A61K 31/519 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 38/26 (2006.01); A61K 38/28 (2006.01); A61K 38/39 (2006.01); A61K 38/51 (2006.01); A61K 39/00 (2006.01); A61P 3/10 (2006.01); A61P 19/04 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); B41J 2/21 (2006.01); H04N 1/60 (2006.01)

CPC (invention and additional information)

A61K 31/519 (2013.01); A61K 39/0008 (2013.01); B41J 2/2107 (2013.01); A61K 2039/542 (2013.01); G06K 2215/0094 (2013.01); G06K 2215/0097 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9832451 A1 19980730; AU 6648898 A 19980818; BR 9807112 A 20010918; CA 2278152 A1 19980730; EP 0994717 A1 20000426; EP 0994717 A4 20000726; HU 0001960 A2 20001028; IL 131025 D0 20010128; JP 2001511134 A 20010807; KR 20000070460 A 20001125; NO 993600 A 19990923; NO 993600 D0 19990723

INPADOC legal status

2001-01-17 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20000801

2000-07-26 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20000614

2000-07-26 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-07-26 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- Free Format Text: 7A 61K 31/505 A, 7A 61K 39/00 B, 7A 61P 37/00 B, 7A 61K 39/00 J, 7A 61K 31:505 J

2000-04-26 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990818

2000-04-26 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE