EP 0994717 A1 20000426 - TREATMENT OF AUTOIMMUNE DISEASE USING TOLERIZATION IN COMBINATION WITH METHOTREXATE

Title (en)

TREATMENT OF AUTOIMMUNE DISEASE USING TOLERIZATION IN COMBINATION WITH METHOTREXATE

Title (de)

BEHANDLUNG VON AUTOIMMUNERKRANKUNGEN ANHAND EINER TOLERANZERHOEHUNG BEWIRKT DURCH DIE KOMBINATION MIT METHOTREXAT

Title (fr)

TRAITEMENT DES MALADIES AUTO-IMMUNES A L'AIDE D'UNE TOLERANCE INDUITE EN COMBINAISON AVEC DU METHOTREXATE

Publication

EP 0994717 A1 20000426 (EN)

Application

EP 98908452 A 19980126

Priority

US 9801648 W 19980126
US 3672297 P 19970124

Abstract (en)

[origin: WO9832451A1] A combination of a mucosally administrable bystander antigen and an orally, enterally, or parenterally administrable methotrexate is employed to make a pharmaceutical formulation and to treat or prevent autoimmune disease. The amounts of bystander antigen and methotrexate are effective in combination to suppress autoimmune response associated with the autoimmune disease.

IPC 1-7

A61K 35/30; A61K 38/00; A61K 38/28; A61K 31/495; A61K 31/50

IPC 8 full level

A61K 31/519 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 38/26 (2006.01); A61K 38/28 (2006.01); C07D 475/08 (2006.01); A61K 38/39 (2006.01); A61K 38/51 (2006.01); A61K 39/00 (2006.01); A61P 3/10 (2006.01); A61P 19/04 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); B41J 2/21 (2006.01); H04N 1/60 (2006.01)

CPC (source: EP KR)

A61K 31/519 (2013.01 - EP); A61K 39/00 (2013.01 - KR); A61K 39/0008 (2013.01 - EP); A61P 3/10 (2018.01 - EP); A61P 19/04 (2018.01 - EP); A61P 27/02 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/06 (2018.01 - EP); B41J 2/2107 (2013.01 - EP); A61K 2039/542 (2013.01 - EP); G06K 2215/0094 (2013.01 - EP); G06K 2215/0097 (2013.01 - EP)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9832451 A1 19980730; AU 6648898 A 19980818; BR 9807112 A 20010918; CA 2278152 A1 19980730; EP 0994717 A1 20000426; EP 0994717 A4 20000726; HU P0001960 A2 20001028; IL 131025 A0 20010128; JP 2001511134 A 20010807; KR 20000070460 A 20001125; NO 993600 D0 19990723; NO 993600 L 19990923

DOCDB simple family (application)

US 9801648 W 19980126; AU 6648898 A 19980126; BR 9807112 A 19980126; CA 2278152 A 19980126; EP 98908452 A 19980126; HU P0001960 A 19980126; IL 13102598 A 19980126; JP 53225298 A 19980126; KR 19997006698 A 19990724; NO 993600 A 19990723