EP 0994953 A1 20000426 - EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS
Title (en)
EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS
Title (de)
EXPRESSION-SYSTEM ZUR HERSTELLUNG VON THERAPEUTISCHER PROTEINE
Title (fr)
SYSTEME D'EXPRESSION POUR LA PRODUCTION DE PROTEINES THERAPEUTIQUES
Publication
Application
Priority
- US 9812777 W 19980619
- US 5035697 P 19970620
Abstract (en)
[origin: WO9859059A1] A novel method is described for expressing biologically functional therapeutic proteins without host cell toxicity. This method takes advantage of the surprising replication activating ability of the 107/402-T antigen. The invention also provides expression vectors, human cells, and fusion proteins for practicing the method. The invention thus provides the art with an expression system for therapeutic proteins which is useful to the pharmaceutical and biotechnology industries.
IPC 1-7
C12N 15/62; C12N 15/69; C12N 15/85; C12N 5/10; C07K 14/72; C07K 14/025
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/12 (2006.01); A61K 35/28 (2006.01); A61K 48/00 (2006.01); C07K 14/025 (2006.01); C07K 14/72 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); C07K 14/005 (2013.01); C07K 14/721 (2013.01); C07K 2319/00 (2013.01); C12N 2710/22022 (2013.01)
Citation (search report)
See references of WO 9859059A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9859059 A1 19981230; AU 4845297 A 19981224; AU 743329 B2 20020124; AU 8074498 A 19990104; CA 2218852 A1 19981220; CA 2294119 A1 19981230; EP 0994953 A1 20000426; JP 2002506350 A 20020226
DOCDB simple family (application)
US 9812777 W 19980619; AU 4845297 A 19971217; AU 8074498 A 19980619; CA 2218852 A 19971218; CA 2294119 A 19980619; EP 98929103 A 19980619; JP 50484699 A 19980619