Global Patent Index - EP 0994953 A1

EP 0994953 A1 20000426 - EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS

Title (en)

EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS

Title (de)

EXPRESSION-SYSTEM ZUR HERSTELLUNG VON THERAPEUTISCHER PROTEINE

Title (fr)

SYSTEME D'EXPRESSION POUR LA PRODUCTION DE PROTEINES THERAPEUTIQUES

Publication

EP 0994953 A1 20000426 (EN)

Application

EP 98929103 A 19980619

Priority

  • US 9812777 W 19980619
  • US 5035697 P 19970620

Abstract (en)

[origin: WO9859059A1] A novel method is described for expressing biologically functional therapeutic proteins without host cell toxicity. This method takes advantage of the surprising replication activating ability of the 107/402-T antigen. The invention also provides expression vectors, human cells, and fusion proteins for practicing the method. The invention thus provides the art with an expression system for therapeutic proteins which is useful to the pharmaceutical and biotechnology industries.

IPC 1-7

C12N 15/62; C12N 15/69; C12N 15/85; C12N 5/10; C07K 14/72; C07K 14/025

IPC 8 full level

A61K 35/12 (2006.01); A61K 35/28 (2006.01); A61K 48/00 (2006.01); C07K 14/025 (2006.01); C07K 14/72 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

A61K 48/00 (2013.01); C07K 14/005 (2013.01); C07K 14/721 (2013.01); C07K 2319/00 (2013.01); C12N 2710/22022 (2013.01)

Citation (search report)

See references of WO 9859059A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9859059 A1 19981230; AU 4845297 A 19981224; AU 743329 B2 20020124; AU 8074498 A 19990104; CA 2218852 A1 19981220; CA 2294119 A1 19981230; EP 0994953 A1 20000426; JP 2002506350 A 20020226

DOCDB simple family (application)

US 9812777 W 19980619; AU 4845297 A 19971217; AU 8074498 A 19980619; CA 2218852 A 19971218; CA 2294119 A 19980619; EP 98929103 A 19980619; JP 50484699 A 19980619