Global Patent Index - EP 0994953 A1

EP 0994953 A1 2000-04-26 - EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS

Title (en)

EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS

Title (de)

EXPRESSION-SYSTEM ZUR HERSTELLUNG VON THERAPEUTISCHER PROTEINE

Title (fr)

SYSTEME D'EXPRESSION POUR LA PRODUCTION DE PROTEINES THERAPEUTIQUES

Publication

EP 0994953 A1 (EN)

Application

EP 98929103 A

Priority

  • US 9812777 W
  • US 5035697 P

Abstract (en)

[origin: WO9859059A1] A novel method is described for expressing biologically functional therapeutic proteins without host cell toxicity. This method takes advantage of the surprising replication activating ability of the 107/402-T antigen. The invention also provides expression vectors, human cells, and fusion proteins for practicing the method. The invention thus provides the art with an expression system for therapeutic proteins which is useful to the pharmaceutical and biotechnology industries.

IPC 1-7 (main, further and additional classification)

C12N 15/62; C07K 14/025; C07K 14/72; C12N 5/10; C12N 15/69; C12N 15/85

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/12 (2006.01); A61K 35/28 (2006.01); A61K 48/00 (2006.01); C07K 14/025 (2006.01); C07K 14/72 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01); C12R 1/91 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); A61K 48/00 (2013.01); C07K 14/721 (2013.01); C07K 2319/00 (2013.01); C12N 2710/22022 (2013.01)

Citation (search report)

See references of WO 9859059A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9859059 A1 19981230; AU 4845297 A 19981224; AU 743329 B2 20020124; AU 8074498 A 19990104; CA 2218852 A1 19981220; CA 2294119 A1 19981230; EP 0994953 A1 20000426; JP 2002506350 A 20020226

INPADOC legal status


2004-04-28 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031022

2003-05-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030411

2000-04-26 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000119

2000-04-26 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE