Global Patent Index - EP 0996429 A1

EP 0996429 A1 20000503 - SOLID STATE SOLUTIONS AND DISPERSIONS OF POORLY WATER SOLUBLE DRUGS

Title (en)

SOLID STATE SOLUTIONS AND DISPERSIONS OF POORLY WATER SOLUBLE DRUGS

Title (de)

FESTE LÖSUNGEN UND DISPERSIONEN VON EINES SCHLECHT WASSERLÖSLICHEN WIRKSTOFFES

Title (fr)

SOLUTIONS A L'ETAT SOLIDE ET DISPERSIONS DE MEDICAMENTS TRES FAIBLEMENT SOLUBLES DANS L'EAU .

Publication

EP 0996429 A1 (EN)

Application

EP 98955458 A

Priority

  • EP 9806544 W
  • US 6333897 P

Abstract (en)

[origin: WO9921534A1] The invention provides a composition useful as a pharmaceutical excipient, the method of producing same, and the pharmaceutical compositions obtained thereby. In particular, the invention has applicability to increasing the solubility of poorly soluble therapeutically active compounds, by means of an excipient comprising a mixture of: (a) saturated polyglycolyzed glycerides, and (b) polyoxypropylene-polyoxyethylene block copolymers, whereby the solubility of the poorly soluble therapeutically active compound in the pharmaceutical composition is enhanced.

IPC 1-7

A61K 9/14

IPC 8 full level

A61K 47/34 (2006.01); A61K 9/14 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/192 (2006.01); A61K 31/4166 (2006.01); A61K 31/4422 (2006.01); A61K 45/00 (2006.01)

CPC (source: EP)

A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01)

Citation (search report)

See references of WO 9921534A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9921534 A1 19990506; AT 232087 T 20030215; CN 1190187 C 20050223; CN 1278164 A 20001227; DE 69811233 D1 20030313; DE 69811233 T2 20031120; DK 0996429 T3 20030526; EP 0996429 A1 20000503; EP 0996429 B1 20030205; ES 2191977 T3 20030916; JP 2001520984 A 20011106; NO 20002133 D0 20000426; NO 20002133 L 20000426; NO 329755 B1 20101213; PT 996429 E 20030630

DOCDB simple family (application)

EP 9806544 W 19981015; AT 98955458 T 19981015; CN 98810593 A 19981015; DE 69811233 T 19981015; DK 98955458 T 19981015; EP 98955458 A 19981015; ES 98955458 T 19981015; JP 2000517694 A 19981015; NO 20002133 A 20000426; PT 98955458 T 19981015