Title (en)

HETEROLOGOUS EXPRESSION OF PROTEINS BY "RESCUED" VECTOR COMPRISING AN INTRON

Title (de)

HETEROLOGE EXPRIMIERUNG VON PROTEINEN MITTELS EINES INTRON ENTHALTENDEN "RESCUED" VECTORS

Title (fr)

EXPRESSION HETEROLOGUE DE PROTEINES A L'AIDE D'UN VECTEUR "SAUVE" COMPRENANT UN INTRON

Publication

EP 0996715 A1 20000503 (EN)

Application

EP 98935143 A 19980717

Priority

• GB 9802130 W 19980717
• GB 9715064 A 19970717

Abstract (en)

[origin: WO9903981A1] A nucleic acid expression construct comprising: (a) a promoter; (b) an intron whose natural position is within the 5'-untranslated region of a gene from which it is derived; (c) a coding sequence; and (d) a 3'-flanking sequence wherein the intron (b) is not derived from the same gene as that from which either the promoter (a) or the protein-coding sequence (c) is derived and processes, vectors, hosts and uses involving such a construct to obtain inter alia an increase in the level of expression of the coding sequence.

IPC 1-7

C12N 15/00; C12N 15/12; C12N 15/85; C12N 5/10; C07K 14/705; C07K 14/78; C07K 14/81; C07K 16/00; A01K 67/027

IPC 8 full level

A01K 67/027 (2006.01); C07K 14/705 (2006.01); C07K 14/78 (2006.01); C07K 14/81 (2006.01); C07K 16/00 (2006.01); C12N 15/85 (2006.01)

CPC (source: EP)

A01K 67/0275 (2013.01); C07K 14/705 (2013.01); C07K 14/78 (2013.01); C07K 14/8125 (2013.01); C07K 16/00 (2013.01); C12N 15/85 (2013.01); C12N 15/8509 (2013.01); A01K 2217/05 (2013.01); A01K 2227/10 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); C12N 2830/008 (2013.01); C12N 2830/42 (2013.01); C12N 2830/85 (2013.01)

Citation (search report)

See references of WO 9903981A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9903981 A1 19990128; WO 9903981 A8 19990422; AU 8450298 A 19990210; EP 0996715 A1 20000503; GB 9715064 D0 19970924

DOCDB simple family (application)

GB 9802130 W 19980717; AU 8450298 A 19980717; EP 98935143 A 19980717; GB 9715064 A 19970717