EP 0996734 A1 20000503 - PLANT TRANSCRIPTION COACTIVATORS WITH HISTONE ACETYLTRANSFERASE ACTIVITY
Title (en)
PLANT TRANSCRIPTION COACTIVATORS WITH HISTONE ACETYLTRANSFERASE ACTIVITY
Title (de)
PFLANZLICHE CO-AKTIVATOREN DER TRANSKRIPTION MIT HISTON-ACETYLTRANSFERASE AKTIVITÄT
Title (fr)
COACTIVATEURS DE TRANSCRIPTION VEGETALE PRESENTANT UNE ACTIVITE D'HISTONE ACETYLTRANSFERASE
Publication
Application
Priority
- US 9812071 W 19980611
- US 4940897 P 19970612
Abstract (en)
[origin: WO9856934A1] This invention relates to isolated nucleic acid fragments encoding all or a substantial portion of a maize, rice, or wheat histone acetyltransferase protein. The invention also relates to the construction of chimeric genes encoding all or a portion of a maize, rice, or wheat histone acetyltransferase protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of maize, rice, or wheat histone acetyltransferase protein in a transformed host cell. The invention also relates to targeting of the maize, rice, or wheat histone acetyltransferase protein to a novel promoter region by the addition of either a DNA-binding domain or a protein-protein interaction domain, to acetylate the core histone, weaken the interaction between core histones and DNA, open up chromatin structure, increase the efficiency of transcriptional initiation, thus leading to a higher level of gene expression.
IPC 1-7
C12N 15/82; C12N 15/29; C12N 9/10; C12Q 1/68; G01N 33/50; A01H 5/00
IPC 8 full level
C12N 9/10 (2006.01); C12N 15/29 (2006.01); C12N 15/82 (2006.01)
CPC (source: EP)
C12N 9/1029 (2013.01); C12N 15/8216 (2013.01)
Citation (search report)
See references of WO 9856934A1
Designated contracting state (EPC)
DE FR GB
DOCDB simple family (publication)
WO 9856934 A1 19981217; AR 012983 A1 20001122; AU 8066398 A 19981230; BR 9809736 A 20001003; EP 0996734 A1 20000503
DOCDB simple family (application)
US 9812071 W 19980611; AR P980102823 A 19980612; AU 8066398 A 19980611; BR 9809736 A 19980611; EP 98928994 A 19980611