EP 0998268 A1 20000510 - POWDER COMPOSITIONS OF UNILAMELLAR LIPOSOMES
Title (en)
POWDER COMPOSITIONS OF UNILAMELLAR LIPOSOMES
Title (de)
PULVERFÖRMIGE ZUSAMMENSETZUNGEN MIT UNILAMELLAREN LIPOSOMEN
Title (fr)
COMPOSITIONS PULVERULENTES DE LIPOSOMES UNILAMELLAIRES
Publication
Application
Priority
- FR 9801203 W 19980611
- FR 9707254 A 19970611
Abstract (en)
[origin: FR2764507A1] The invention concerns powder compositions of stabilised unilamellar liposomes, comprising at least an external lipid phase and a internal aqueous polar nucleus gelled at room temperature, the method for preparing them and their applications as nutritional additives and in pharmaceutical compositions to be orally administered (with action against lipemia). Said compositions essentially consist of unilamellar liposomes comprising an external lipid phase consisting of class 4 lipids (phospholipids) and an internal aqueous nucleus consisting essentially of a mixture M of at least two different non-polymerisable gelling agents (G1 and G2) whereof the gel-sol phase transition point is not less than 37 DEG C, G1 being a gelling agent selected among gelatines and carrageenans and G2 being selected among carrageenans with properties different from the carrageenans selected for G1, and celluloses, which liposomes have a diameter ranging between 20 nm and 1 mm, preferably ranging between 50 nm and 500 nm and having the form of particulate units with an average particle diameter between 10 mm and 1000 mm, formed by one or several of said liposomes, enclosed in a sheath selected in the group consisting of a dehydrated thermoreversible aqueous gel identical to said internal nucleus aqueous gel, dextrins or a mixture thereof, such that they contain, on an average, 10<16> to 10<18> liposomes per gram of powder.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 9/133 (2006.01); A61K 31/685 (2006.01)
CPC (source: EP KR US)
A61K 9/127 (2013.01 - EP KR US); A61K 9/1277 (2013.01 - EP US); A61K 31/685 (2013.01 - EP US); Y10S 977/907 (2013.01 - EP US); Y10T 428/2984 (2015.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 6331315 B1 20011218; AU 738238 B2 20010913; AU 738238 C 20030703; AU 8112298 A 19981230; BR 9810104 A 20000808; CN 1264296 A 20000823; EP 0998268 A1 20000510; FR 2764507 A1 19981218; FR 2764507 B1 20001020; HU P0002066 A2 20001028; HU P0002066 A3 20011228; JP 2002511077 A 20020409; KR 20010013664 A 20010226; PL 337782 A1 20000911; RU 2214231 C2 20031020; WO 9856351 A1 19981217
DOCDB simple family (application)
US 44544100 A 20000216; AU 8112298 A 19980611; BR 9810104 A 19980611; CN 98807282 A 19980611; EP 98930819 A 19980611; FR 9707254 A 19970611; FR 9801203 W 19980611; HU P0002066 A 19980611; JP 50178399 A 19980611; KR 19997011676 A 19991210; PL 33778298 A 19980611; RU 2000100955 A 19980611