Global Patent Index - EP 0998268 A1

EP 0998268 A1 2000-05-10 - POWDER COMPOSITIONS OF UNILAMELLAR LIPOSOMES

Title (en)

POWDER COMPOSITIONS OF UNILAMELLAR LIPOSOMES

Title (de)

PULVERFÖRMIGE ZUSAMMENSETZUNGEN MIT UNILAMELLAREN LIPOSOMEN

Title (fr)

COMPOSITIONS PULVERULENTES DE LIPOSOMES UNILAMELLAIRES

Publication

EP 0998268 A1 (FR)

Application

EP 98930819 A

Priority

  • FR 9801203 W
  • FR 9707254 A

Abstract (en)

[origin: FR2764507A1] The invention concerns powder compositions of stabilised unilamellar liposomes, comprising at least an external lipid phase and a internal aqueous polar nucleus gelled at room temperature, the method for preparing them and their applications as nutritional additives and in pharmaceutical compositions to be orally administered (with action against lipemia). Said compositions essentially consist of unilamellar liposomes comprising an external lipid phase consisting of class 4 lipids (phospholipids) and an internal aqueous nucleus consisting essentially of a mixture M of at least two different non-polymerisable gelling agents (G1 and G2) whereof the gel-sol phase transition point is not less than 37 DEG C, G1 being a gelling agent selected among gelatines and carrageenans and G2 being selected among carrageenans with properties different from the carrageenans selected for G1, and celluloses, which liposomes have a diameter ranging between 20 nm and 1 mm, preferably ranging between 50 nm and 500 nm and having the form of particulate units with an average particle diameter between 10 mm and 1000 mm, formed by one or several of said liposomes, enclosed in a sheath selected in the group consisting of a dehydrated thermoreversible aqueous gel identical to said internal nucleus aqueous gel, dextrins or a mixture thereof, such that they contain, on an average, 10<16> to 10<18> liposomes per gram of powder.

IPC 1-7 (main, further and additional classification)

A61K 9/127; A61K 31/685

IPC 8 full level (invention and additional information)

A61K 9/127 (2006.01); A61K 9/133 (2006.01); A61K 31/685 (2006.01)

CPC (invention and additional information)

A61K 31/685 (2013.01); A61K 9/127 (2013.01); A61K 9/1277 (2013.01); Y10S 514/824 (2013.01); Y10S 977/907 (2013.01); Y10T 428/2984 (2013.01)

Citation (search report)

See references of WO 9856351A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2764507 A1 19981218; FR 2764507 B1 20001020; AU 738238 B2 20010913; AU 738238 C 20030703; AU 8112298 A 19981230; BR 9810104 A 20000808; CN 1264296 A 20000823; EP 0998268 A1 20000510; HU 0002066 A2 20001028; HU 0002066 A3 20011228; JP 2002511077 A 20020409; KR 20010013664 A 20010226; PL 337782 A1 20000911; RU 2214231 C2 20031020; US 6331315 B1 20011218; WO 9856351 A1 19981217

INPADOC legal status


2005-04-27 [18W] WITHDRAWN

- Effective date: 20050228

2000-05-10 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000107

2000-05-10 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE