EP 0998293 A1 20000510 - CYTOKINE RELATED TREATMENTS OF DISEASE
Title (en)
CYTOKINE RELATED TREATMENTS OF DISEASE
Title (de)
BEHANDLUNGEN VON ZYTOKIN-BEDINGTEN KRANKHEITEN
Title (fr)
TRAITEMENTS LIES A LA CYTOKINE DESTINES A DES AFFECTIONS
Publication
Application
Priority
- US 9800634 W 19980113
- US 3609497 P 19970117
- US 2858697 P 19970423
- US 4397497 P 19970423
- US 5548797 P 19970812
Abstract (en)
[origin: WO9830223A1] Nucleosides and other compounds to selectively modulate Th1 and Th2 responses relative to each other in the treatment of disease. In one aspect of the invention, administration of a nucleoside or other compound reduces the dosage at which a primary drug is administered. In another aspect of the invention, an abnormality reflected in increased response in one group of cytokines is treated by administering a nucleoside or other compound which increases response in another group of cytokines. In yet another aspect of the invention, a patient is prophylactically treated by administering a nucleoside or other compound which selectively reduces Th1 activity without significantly reducing Th2 activity. In yet another aspect of the invention, a nucleoside or other compound is administered to a patient at a dose which reduces the patient's GTP pool to a degree that selectively reduces one of the Th1 or Th2 response without significantly reducing the other response. Controlled release dosage forms are particularly contemplated to achieve that result.
IPC 1-7
IPC 8 full level
A61K 31/52 (2006.01); C07H 19/167 (2006.01); A61K 31/522 (2006.01); A61K 31/56 (2006.01); A61K 31/70 (2006.01); A61K 31/7042 (2006.01); A61K 31/7052 (2006.01); A61K 31/7056 (2006.01); A61K 31/7076 (2006.01); A61K 31/708 (2006.01); A61K 31/7115 (2006.01); A61K 45/06 (2006.01); A61P 1/16 (2006.01); A61P 3/10 (2006.01); A61P 17/00 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 37/04 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07H 19/00 (2006.01); C07H 19/04 (2006.01); C07H 19/052 (2006.01); C07H 19/056 (2006.01); C07H 19/16 (2006.01); C07H 19/24 (2006.01)
CPC (source: EP KR)
A61K 31/52 (2013.01 - EP); A61K 31/522 (2013.01 - EP); A61K 31/70 (2013.01 - EP KR); A61K 31/7056 (2013.01 - EP); A61K 31/7076 (2013.01 - EP); A61K 31/7115 (2013.01 - EP); A61K 45/06 (2013.01 - EP); A61P 1/16 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 17/00 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 37/02 (2018.01 - EP); A61P 37/04 (2018.01 - EP); A61P 37/08 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07H 19/00 (2013.01 - EP); C07H 19/04 (2013.01 - EP); C07H 19/052 (2013.01 - EP); C07H 19/056 (2013.01 - EP); C07H 19/16 (2013.01 - EP); C07H 19/24 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9830223 A1 19980716; AU 6023898 A 19980803; AU 736075 B2 20010726; BR 9807473 A 20000321; CA 2278158 A1 19980716; CN 1253504 A 20000517; CN 1289594 A 20010404; CN 1312254 A 20010912; EP 0998293 A1 20000510; EP 0998293 A4 20020717; HU P0001526 A2 20010528; HU P0001526 A3 20021028; IL 130497 A0 20000601; JP 2002080490 A 20020319; JP 2002515892 A 20020528; JP 2004035546 A 20040205; KR 20000070167 A 20001125; NO 20004327 D0 20000831; NO 20004327 L 19990913; NO 20004329 D0 20000831; NO 20004329 L 19990913; NO 993439 D0 19990713; NO 993439 L 19990913; PL 336579 A1 20000703; SI 9820003 A 19990630; SK 94099 A3 20010611; YU 61598 A 20030228
DOCDB simple family (application)
US 9800634 W 19980113; AU 6023898 A 19980113; BR 9807473 A 19980113; CA 2278158 A 19980113; CN 00121912 A 20000722; CN 00126807 A 20000829; CN 98801801 A 19980113; EP 98903474 A 19980113; HU P0001526 A 19980113; IL 13049798 A 19980113; JP 2001155321 A 20010524; JP 2003115258 A 20030421; JP 53124598 A 19980113; KR 19997006393 A 19990714; NO 20004327 A 20000831; NO 20004329 A 20000831; NO 993439 A 19990713; PL 33657998 A 19980113; SI 9820003 A 19980113; SK 94099 A 19980113; YU 61598 A 19980113