EP 0998669 A1 20000510 - IN-VITRO DETECTION OF REACTIONS IN BLOOD TO FOREIGN SUBSTANCES
Title (en)
IN-VITRO DETECTION OF REACTIONS IN BLOOD TO FOREIGN SUBSTANCES
Title (de)
IN VITRO NACHWEIS VON FREMDSTOFFREAKTIONEN IM BLUT
Title (fr)
DETECTION IN-VITRO DE REACTIONS A DES SUBSTANCES ETRANGERES DANS LE SANG
Publication
Application
Priority
- US 9704849 W 19970325
- US 1406096 P 19960325
Abstract (en)
[origin: WO9736169A1] The present invention is a method of detecting reaction in blood caused by the presence of a foreign substance in the blood, comprising the steps of: establishing a potential across a predetermined spatial volume; passing a first portion of the blood through the predetermined spatial volume; substantially continuously measuring the potential across the predetermined spatial volume over a first predetermined period of time; comparing the measured potential with a baseline; and calculating the total volume of solids in the first portion of the blood as a function of a total absolute deviation of the measured potential from the baseline. The same procedure is then followed with a second portion of the blood, after it has been exposed to the substance whose reaction is being determined. The two calculations are then compared, with a positive reaction being indicated when the two measured solid volumes are measurably different. The baselines are preferably dynamic baselines, and are determined with reference to the starting point of a sharp rise in the measured potential.
IPC 1-7
IPC 8 full level
G01N 15/12 (2006.01); G01N 27/02 (2006.01); G01N 33/487 (2006.01)
CPC (source: EP)
G01N 15/12 (2013.01); G01N 33/48714 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9736169 A1 19971002; AU 2589597 A 19971017; EP 0998669 A1 20000510; EP 0998669 A4 20041117
DOCDB simple family (application)
US 9704849 W 19970325; AU 2589597 A 19970325; EP 97917620 A 19970325