Global patent index - EP 0998669 A1

EP 0998669 A1 2000-05-10 - IN-VITRO DETECTION OF REACTIONS IN BLOOD TO FOREIGN SUBSTANCES

Title (en)

IN-VITRO DETECTION OF REACTIONS IN BLOOD TO FOREIGN SUBSTANCES

Title (de)

IN VITRO NACHWEIS VON FREMDSTOFFREAKTIONEN IM BLUT

Title (fr)

DETECTION IN-VITRO DE REACTIONS A DES SUBSTANCES ETRANGERES DANS LE SANG

Publication

EP 0998669 A1 (EN)

Application

EP 97917620 A

Priority

  • US 9704849 W
  • US 1406096 P

Abstract (en)

[origin: WO9736169A1] The present invention is a method of detecting reaction in blood caused by the presence of a foreign substance in the blood, comprising the steps of: establishing a potential across a predetermined spatial volume; passing a first portion of the blood through the predetermined spatial volume; substantially continuously measuring the potential across the predetermined spatial volume over a first predetermined period of time; comparing the measured potential with a baseline; and calculating the total volume of solids in the first portion of the blood as a function of a total absolute deviation of the measured potential from the baseline. The same procedure is then followed with a second portion of the blood, after it has been exposed to the substance whose reaction is being determined. The two calculations are then compared, with a positive reaction being indicated when the two measured solid volumes are measurably different. The baselines are preferably dynamic baselines, and are determined with reference to the starting point of a sharp rise in the measured potential.

IPC 1-7 (main, further and additional classification)

G01N 27/02; G01N 27/04; G01N 33/487

IPC 8 full level (invention and additional information)

G01N 15/12 (2006.01); G01N 27/02 (2006.01); G01N 33/487 (2006.01)

CPC (invention and additional information)

G01N 33/48714 (2013.01); G01N 15/12 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9736169 A1 19971002; AU 2589597 A 19971017; EP 0998669 A1 20000510; EP 0998669 A4 20041117

INPADOC legal status

2006-08-09 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20051004

2004-11-17 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20041005

2004-11-17 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7G 01N 27/02 A

2004-11-17 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7G 01N 27/04 B

2004-11-17 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- IPC: 7G 01N 33/487 B

2000-05-10 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19981211

2000-05-10 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-05-10 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 19981022;LT PAYMENT 19981022;LV PAYMENT 19981022;RO PAYMENT 19981022;SI PAYMENT 19981022