EP 1000036 A1 20000517 - HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE
Title (en)
HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE
Title (de)
HYDANTOINDERIVATE MIT FARNESYLTRANSFERASE HEMMENDER AKTIVITÄT
Title (fr)
DERIVES D'HYDANTOINE DOTES D'UNE ACTIVITE INHIBITRICE VIS A VIS DE LA FARNESYLE TRANSFERASE
Publication
Application
Priority
- KR 9800225 W 19980724
- KR 19970035333 A 19970726
Abstract (en)
[origin: WO9905117A1] The present invention relates to novel hydantoin derivatives represented by formula (I) which shows an inhibitory activity against farnesyl transferase, and thus can be used as an anti-cancer agent, or pharmaceutically acceptable salts thereof, in which R1, R2, R3 and R4 are defined as described below. The present invention also relates to a process for preparation of the compound of formula (I), and to an anti-cancer composition comprising the compound of formula (I) as an active ingredient.
IPC 1-7
IPC 8 full level
A61K 31/4178 (2006.01); A61K 31/427 (2006.01); A61K 31/4427 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/5355 (2006.01); A61K 31/541 (2006.01); A61P 35/00 (2006.01); C07D 233/74 (2006.01); C07D 233/76 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP KR)
A61P 19/02 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07D 233/72 (2013.01 - KR); C07D 233/74 (2013.01 - KR); C07D 233/76 (2013.01 - EP); C07D 277/22 (2013.01 - KR); C07D 333/24 (2013.01 - KR); C07D 401/14 (2013.01 - EP); C07D 403/06 (2013.01 - KR); C07D 405/14 (2013.01 - EP); C07D 409/14 (2013.01 - EP KR); C07D 417/14 (2013.01 - EP KR)
Citation (search report)
See references of WO 9905117A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9905117 A1 19990204; AR 015412 A1 20010502; AU 729341 B2 20010201; AU 8464798 A 19990216; EP 1000036 A1 20000517; JP 2001510829 A 20010807; KR 100384116 B1 20030830; KR 19990012061 A 19990225; KR 19990014070 A 19990225; ZA 986623 B 19990126
DOCDB simple family (application)
KR 9800225 W 19980724; AR P980103683 A 19980727; AU 8464798 A 19980724; EP 98935376 A 19980724; JP 2000504116 A 19980724; KR 19970035333 A 19970726; KR 19980029459 A 19980722; ZA 986623 A 19980724