EP 1000044 A1 20000517 - BENZOTHIA(OXA)DIAZOL DERIVATIVES AND THEIR USE AS ENDOTHELIN-RECEPTOR ANTAGONISTS
Title (en)
BENZOTHIA(OXA)DIAZOL DERIVATIVES AND THEIR USE AS ENDOTHELIN-RECEPTOR ANTAGONISTS
Title (de)
BENZOTHIA(OXA)DIAZOLDERIVATE UND IHRE VERWENDUNG ALS ENDOTHELIN-REZEPTOR-ANTAGONISTEN
Title (fr)
DERIVES DE BENZOTHIA(OXA)DIAZOL ET LEUR UTILISATION COMME ANTAGONISTES DES RECEPTEURS DE L'ENDOTHELINE
Publication
Application
Priority
- DE 19731571 A 19970723
- EP 9803957 W 19980629
Abstract (en)
[origin: DE19731571A1] The invention relates to novel compounds of formula (I), wherein R represents group (1), X stands for O or S, and R1, R2, R3, R4, R5 and R6 have the meaning cited in Claim 1, or a tauomeric cyclized form. The invention further relates to (E) isomers and their salts. Said novel derivatives exhibit endothelin-receptor antagonistic properties.
IPC 1-7
C07D 285/14; C07D 271/12; C07D 417/04; C07D 413/04; A61K 31/41
IPC 8 full level
A61K 31/4245 (2006.01); A61K 31/433 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/06 (2006.01); A61P 13/08 (2006.01); A61P 13/12 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C07D 271/12 (2006.01); C07D 285/14 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01)
CPC (source: EP US)
A61P 9/04 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 9/12 (2018.01 - EP); A61P 11/06 (2018.01 - EP); A61P 13/08 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 25/00 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 271/12 (2013.01 - EP US); C07D 285/14 (2013.01 - EP US); C07D 413/04 (2013.01 - EP US); C07D 417/04 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
US 6197800 B1 20010306; AR 010933 A1 20000712; AU 733338 B2 20010510; AU 8802298 A 19990216; BR 9811537 A 20000829; CA 2297315 A1 19990204; CN 1265102 A 20000830; DE 19731571 A1 19990128; EP 1000044 A1 20000517; HU P0003335 A2 20010730; ID 22978 A 19991223; JP 2001510836 A 20010807; KR 20010022004 A 20010315; NO 20000324 D0 20000121; NO 20000324 L 20000121; PL 338070 A1 20000925; SK 512000 A3 20000711; TW 461887 B 20011101; WO 9905132 A1 19990204; ZA 986551 B 19990920
DOCDB simple family (application)
US 46331100 A 20000327; AR P980103582 A 19980722; AU 8802298 A 19980629; BR 9811537 A 19980629; CA 2297315 A 19980629; CN 98807549 A 19980629; DE 19731571 A 19970723; EP 9803957 W 19980629; EP 98939552 A 19980629; HU P0003335 A 19980629; ID 991588 A 19990422; JP 2000504129 A 19980629; KR 20007000571 A 20000118; NO 20000324 A 20000121; PL 33807098 A 19980629; SK 512000 A 19980629; TW 87111803 A 19980720; ZA 986551 A 19980722