Global Patent Index - EP 1000055 A1

EP 1000055 A1 2000-05-17 - SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS

Title (en)

SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS

Title (de)

SUBSTITUIERTE PYRAZOLE ALS P38-KINASE-INHIBITOREN

Title (fr)

PYRAZOLES SUBSTITUES UTILISES COMME INHIBITEURS DE p38 KINASE

Publication

EP 1000055 A1 (EN)

Application

EP 98923642 A

Priority

  • US 9810436 W
  • US 4757097 P

Abstract (en)

[origin: WO9852940A1] A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (I) wherein R<1>, R<2>, R<3> and R<4> are as described in the specification.

IPC 1-7 (main, further and additional classification)

C07D 401/04; A61K 31/415; A61K 31/44; A61K 31/505; C07D 401/14; C07D 405/14; C07D 409/14; C07D 413/14; C07D 417/14; C07D 453/02; C07D 471/04

IPC 8 full level (invention and additional information)

C07D 473/00 (2006.01); A61K 31/4155 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 31/506 (2006.01); A61K 31/52 (2006.01); A61K 31/5377 (2006.01); A61P 1/04 (2006.01); A61P 3/14 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); A61P 19/06 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 451/02 (2006.01); C07D 453/02 (2006.01); C07D 471/04 (2006.01)

CPC (invention and additional information)

C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 453/02 (2013.01); C07D 471/04 (2013.01)

Citation (search report)

See references of WO 9852940A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9852940 A1 19981126; AP 1246 A 20040207; AP 9901715 A0 19991231; AU 754830 B2 20021128; AU 754830 C 20040212; AU 7588398 A 19981211; BG 103964 A 20000831; BG 64313 B1 20040930; BR 9809147 A 20000801; CA 2291115 A1 19981126; CN 1264377 A 20000823; EA 003925 B1 20031030; EA 199900953 A1 20001030; EE 9900527 A 20000615; EP 1000055 A1 20000517; GE P20033053 B 20030210; HU 0001880 A2 20010328; HU 0001880 A3 20020328; ID 22982 A 19991223; IL 132991 A 20051120; IL 132991 D0 20010319; IS 5257 A 19991119; JP 2002508754 A 20020319; KR 20010012854 A 20010226; NO 995695 A 20000121; NO 995695 D0 19991119; NZ 501112 A 20021025; OA 12981 A 20061013; PL 337020 A1 20000731; SK 157899 A3 20000814; TR 200000235 T2 20000522; ZA 9804358 B 19990524

INPADOC legal status


2010-02-24 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20090822

2007-05-09 [R17C] DATE OF DESPATCH OF FIRST EXAMINATION REPORT

- Effective date: 20020313

2006-10-18 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: G.D. SEARLE LLC

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: ANANTANARAYAN, ASHOK

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: CLARE, MICHAEL

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: COLLINS, PAUL, W.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: CRICH, JOYCE, ZUOWU

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: DEVRAJ, RAJESH

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: FLYNN, DANIEL, L.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: GENG, LIFENG

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: HANSON, GUNNAR, J.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KOSZYK, FRANCIS, J.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: LIAO, SHUYUAN

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: PARTIS, RICHARD, A.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: RAO, SHASHIDHAR, N.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: SELNESS, SHAUN, RAJ

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: SOUTH, MICHAEL, S.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: STEALEY, MICHAEL, A.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: WEIER, RICHARD, M.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: XU, XIANGDONG

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: KHANNA, ISH K.

2003-11-05 [RIN1] INVENTOR (CORRECTION)

- Inventor name: YU, YI

2002-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020313

2000-05-17 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991217

2000-05-17 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-05-17 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 19991217;LT PAYMENT 19991217;LV PAYMENT 19991217;MK PAYMENT 19991217;RO PAYMENT 19991217;SI PAYMENT 19991217